Distribution of type IV collagen subtypes in human testes and their association with spermatogenesis  Masaki Dobashi, M.D., Masato Fujisawa, M.D., Ichiro Naito, M.D., Takafumi Yamazaki, M.D., Hiroshi Okada, M.D., Sadao Kamidono, M.D.  Fertility and Sterility  Volume 80, Pages 755-760 (September 2003) DOI: 10.1016/S0015-0282(03)00775-1

FIGURE 1 Distribution of α1(IV), α2(IV), α3(IV), α4(IV), α5(IV), α6(IV) chains, and negative control in normal testes. (A) α1(IV); (B) α2(IV); (C) α3(IV); (D) α4(IV); (E) α5(IV); (F) α6(IV); (G) negative control. Original magnification, ×100; bar = 20 μm. Dobashi. Type IV collagen subtypes in human testes. Fertil Steril 2003. Fertility and Sterility 2003 80, 755-760DOI: (10.1016/S0015-0282(03)00775-1)

FIGURE 2 Distribution of α1(IV), α2(IV) chains, and negative control in testes with varicocele. (A) α1(IV); (B) α2(IV); (C) negative control. Original magnification, ×200; bar = 50 μm. Dobashi. Type IV collagen subtypes in human testes. Fertil Steril 2003. Fertility and Sterility 2003 80, 755-760DOI: (10.1016/S0015-0282(03)00775-1)

FIGURE 3 Distribution of α1(IV), α2(IV) chains, and negative control in testes with SCO. (A) α1(IV); (B) α2(IV); (C) negative control. Original magnification, ×200; bar = 50 μm. Dobashi. Type IV collagen subtypes in human testes. Fertil Steril 2003. Fertility and Sterility 2003 80, 755-760DOI: (10.1016/S0015-0282(03)00775-1)

FIGURE 4 Collagen IV index for α1(IV) chain in patients with normal testes, varicocele, and SCO. *P<.01, significant difference; **P<.001, significant difference. Dobashi. Type IV collagen subtypes in human testes. Fertil Steril 2003. Fertility and Sterility 2003 80, 755-760DOI: (10.1016/S0015-0282(03)00775-1)

FIGURE 5 Collagen IV index for α2(IV) chain in patients with normal testes, varicocele, and SCO. *P<.01, significant difference; ***P<.05, significant difference. Dobashi. Type IV collagen subtypes in human testes. Fertil Steril 2003. Fertility and Sterility 2003 80, 755-760DOI: (10.1016/S0015-0282(03)00775-1)