Plasma adenosine concentration increases during exercise: A possible contributing factor in exercise-induced bronchoconstriction in asthma Éva Vizi,

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Presentation transcript:

Plasma adenosine concentration increases during exercise: A possible contributing factor in exercise-induced bronchoconstriction in asthma Éva Vizi, MD, Éva Huszár, PhD, Zsuzsa Csoma, MD, György Böszörményi-Nagy, MD, PhD, Erzsébet Barát, PhD, Ildikó Horváth, MD, PhD, Irén Herjavecz, MD, PhD, Márk Kollai, MD, PhD Journal of Allergy and Clinical Immunology Volume 109, Issue 3, Pages 446-448 (March 2002) DOI: 10.1067/mai.2002.121955 Copyright © 2002 Mosby, Inc. Terms and Conditions

Fig. 1 Individual and mean (± 1 SD) values of FEV1 and concentrations of ADO in healthy volunteers (Control) and patients with asthma (Patient) before (B) and after (PE) exercise. Differences in FEV1% and/or ADO within groups: *P < .05; ***P < .001. Differences in FEV1% and/or ADO between groups: ΔP < .05; ΔΔΔP < .001. Journal of Allergy and Clinical Immunology 2002 109, 446-448DOI: (10.1067/mai.2002.121955) Copyright © 2002 Mosby, Inc. Terms and Conditions

Fig. 2 A, Relationship between increase in ADO and percent fall in SaO2 in patients with asthma (r 2 = 0.693; P < .05). B, Relationship between percent fall in FEV1 and increase in ADO in patients with asthma (r 2 = 0.475; P < .05). Journal of Allergy and Clinical Immunology 2002 109, 446-448DOI: (10.1067/mai.2002.121955) Copyright © 2002 Mosby, Inc. Terms and Conditions