Analytic framework illustrating exposure to preventive measures that reduce the risk of transmission between HIV-serodiscordant sex partners. Analytic.

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Presentation transcript:

Analytic framework illustrating exposure to preventive measures that reduce the risk of transmission between HIV-serodiscordant sex partners. Analytic framework illustrating exposure to preventive measures that reduce the risk of transmission between HIV-serodiscordant sex partners. The numbers in the corresponding pathways illustrate the risk of HIV transmission from the HIV-positive partner to the HIV-negative partner during sex for Q1 to Q5. Note: Q1 = to determine risk when a sex partner who is HIV-positive is taking antiretroviral therapy (with varying levels of viral load); Q2 = to determine risk when a sex partner who is HIV-positive is taking antiretroviral therapy and has a suppressed viral load; Q3 = to determine risk when a sex partner who is HIV-positive is taking antiretroviral therapy and either partner uses condoms (or other barrier methods); Q4 = to determine risk when a sex partner who is HIV-positive is taking antiretroviral therapy and has a suppressed viral load, and either partner uses condoms (or other barrier methods); Q5 = to determine risk when either partner uses condoms (or barrier methods) alone. Jennifer LeMessurier et al. CMAJ 2018;190:E1350-E1360 ©2018 by Canadian Medical Association