NK cell function of spleen MNCs (A) and NK cell frequencies in the ileum, duodenum, and spleen (B) of protein-deficient and -sufficient HIFM/HRV-infected.

Slides:

Advertisements

Similar presentations

Th9 Cells Drive Host Immunity against Gastrointestinal Worm Infection

Advertisements

Expression of α5β1-integrin enhances EboV GP-mediated infection of GD25 cells. Expression of α5β1-integrin enhances EboV GP-mediated infection of GD25.

A novel immunoregulatory role for NK-cell cytotoxicity in protection from HLH-like immunopathology in mice by Fernando E. Sepulveda, Sophia Maschalidi,

Primary human MNCs and MDMs are targets of ZIKV infection.

by Norman Nausch, Ioanna E

TriKE stimulates NK-cell function to overcome myeloid-derived suppressor cells in MDS by Dhifaf Sarhan, Ludwig Brandt, Martin Felices, Karolin Guldevall,

Attenuated MDSC-suppressive activity and metastasis development in IDO-deficient mice is rescued by IL-6. Attenuated MDSC-suppressive activity and metastasis.

Fig. 2. Mechanism of PD-L1 down-regulation in NOD HSPCs.

by Cunren Liu, Shaohua Yu, John Kappes, Jianhua Wang, William E

Bay induced aggregation of Cp occurs in HBV-infected HepG2-NTCP cells.

MFS1 expression in IPO323 MFS1 replacement mutants.

Volume 24, Issue 5, Pages (November 2013)

Volume 23, Issue 7, Pages (May 2018)

MFS1 expression in parental and progeny strains.

MFS1 expression in Z. tritici field isolates with different promoter genotypes. MFS1 expression in Z. tritici field isolates with different promoter genotypes.

Volume 33, Issue 1, Pages (July 2010)

Commensal bacteria reduce the stability of influenza A virus.

Stanford L Peng, Andrea J Gerth, Ann M Ranger, Laurie H Glimcher

FLC treatment results in an increase in ploidy in a significant fraction of cells. FLC treatment results in an increase in ploidy in a significant fraction.

Volume 23, Issue 1, Pages (January 2015)

Fig. 2. IL-2/rapamycin–expanded T cells express homing receptors to traffic to lymphoma sites and are resistant to SN-38 toxicity. IL-2/rapamycin–expanded.

Volume 17, Issue 2, Pages (February 2009)

TriKE–treated NK cells overcome MDSC-induced immune suppression.

Silencing Ifngr1 in the CMT167 line confers decreased response to IFNγ in vitro and in vivo. Silencing Ifngr1 in the CMT167 line confers decreased response.

Ag 85A–specific immune responses.

Volume 38, Issue 6, Pages (June 2013)

Effect of CD4+ Th1 cytokines and HER2-targeted antibodies on MHC class I restoration and HER2369–377-CD8+ T-cell targeting of HER2-expressing cancer cells.

Immune cell recruitment after the NIR-boosted and MN-mediated cancer immunotherapy. Immune cell recruitment after the NIR-boosted and MN-mediated cancer.

Increased reconstitution of human NK cells in NSG hIL-7xhIL-15 humanized mice. Increased reconstitution of human NK cells in NSG hIL-7xhIL-15 humanized.

Fold changes in CgA, MUC2, PCNA, SOX9, and villin mRNA levels in IECs of deficient-diet HIFM/HRV-infected versus deficient-diet HRV-infected pigs (A) and.

Socs1 KD tumors exhibit a more T cell–inflamed phenotype and increased CD8+ T cell activation. Socs1 KD tumors exhibit a more T cell–inflamed phenotype.

Normalized weight gain of protein-sufficient and -deficient pigs after HRV inoculation and HIFM transplantation monitored over a period of 4 weeks. Normalized.

E. coli CFT073 and E. coli MG1655 persistence.

PTX in combination with PLX397 induces antitumor T-cell response.

The number of islet antigen–specific T cells is reduced in CT-treated RIP-LCMV-GP mice. The number of islet antigen–specific T cells is reduced in CT-treated.

SAM transport by Gap4 in S. cerevisiae cells.

Analysis of tumor-infiltrating CD8+ T cells and effect of T and NK cell depletion. Analysis of tumor-infiltrating CD8+ T cells and effect of T and NK cell.

Comparison of A2-CMVpp65495–503 and A2-PPI15–24 CD8 T-cell clones killing of cognate peptide-pulsed targets and granule content. Comparison of A2-CMVpp65495–503.

Therapeutic effect of IL-12/ms treatment on gonococcal infection depends on both IFN-γ and B cells. Therapeutic effect of IL-12/ms treatment on gonococcal.

Fold changes in CgA, MUC2, PCNA, SOX9, and villin mRNA levels in IECs of deficient- versus sufficient-diet HIFM/HRV-infected pigs (A), of deficient- versus.

Assessing the effect of TNF-α and TRAIL on A2-PPI15–24 CD8 T-cell cytotoxicity. Assessing the effect of TNF-α and TRAIL on A2-PPI15–24 CD8 T-cell cytotoxicity.

CD25 surface expression and TCR signal strength predict T helper differentiation and memory potential of early effector T cells in vivo. CD25 surface expression.

Functional microbiome differences between high-fat and standard chow diets. Functional microbiome differences between high-fat and standard chow diets.

by Martin Felices, Behiye Kodal, Peter Hinderlie, Michael F

Overexpression of IL-27 upregulates expression of multiple IR by T cells in vivo. Overexpression of IL-27 upregulates expression of multiple IR by T cells.

Reduced tumor growth in CCR5-deficient mice is associated with perturbed killing ability of Treg cells. Reduced tumor growth in CCR5-deficient mice is.

Wolbachia bacterial infection does not affect the expression of Imd pathway components and ROS-producing oxidases. Wolbachia bacterial infection does not.

Possible mechanisms of recognition of MHCIlow tumor cells by NSCs

Stereotactic radiotherapy increases Tregs in tumors.

DCH-mediated cytotoxicity of isolated CD4+ and CD8+ T cells.

CD4+ memory T cells derived from either CD25hi or CD25lo effector cells respond robustly to secondary challenge. CD4+ memory T cells derived from either.

CD25 expression predicts effector and memory differentiation.

PBMC- and T cell-dependent cytotoxic activity of DCH and variant proteins. PBMC- and T cell-dependent cytotoxic activity of DCH and variant proteins. A.

Overexpression of DDB2 reduces invasive abilities in lungs of aggressive breast tumor cells. Overexpression of DDB2 reduces invasive abilities in lungs.

NK activity in healthy donors (n=51) and patients with FRH upon recurrence (n=28) and remission (n=23). NK activity in healthy donors (n=51) and patients.

Colony formation of K-562 cells after 24 h (upper panel) or 48 h (lower panel) exposure to ErPC3 (20 μm) and ASO-bcr (10 μm), respectively. Colony formation.

Normalized abundance of tetracycline resistance genes in Swedish infants by AMR++. Normalized abundance of tetracycline resistance genes in Swedish infants.

The CD8+ cytotoxic T-cell response in Ron TK−/− hosts in response to tumors is necessary and sufficient to block metastasis. The CD8+ cytotoxic T-cell.

The effect of TGFβ on the post-RT increase of Tregs in tumors.

IL35 regulation of tumor growth is accompanied by suppression of CD4+ effector T-cell activity and expansion of Tregs. IL35 regulation of tumor growth.

Volume 37, Issue 2, Pages (August 2012)

The effect of βAR signaling on the generation of a cytotoxic CD8+ T-cell response in vivo. The effect of βAR signaling on the generation of a cytotoxic.

Mice with a B cell–specific deletion of Ets1 do not have increased CD4+ T cell activation. Mice with a B cell–specific deletion of Ets1 do not have increased.

Amino acids are required for completion of SS differentiation and cell viability in very-low-glucose medium. Amino acids are required for completion of.

IL-9–expressing TH cells are highly enriched in CCR4+/CCR8+ effector memory TH cells. IL-9–expressing THcells are highly enriched in CCR4+/CCR8+effector.

Fig. 5 Effector function of MIH5 isotype variants.

Total ARG reads normalized by read length and 16S gene read count in early life in Bangladesh. Total ARG reads normalized by read length and 16S gene read.

GBM cells infected in vitro with HCMV divide less often than uninfected cells do. GBM cells infected in vitro with HCMV divide less often than uninfected.

GBM 112 and GBM 144 cells infected in vitro with HCMV resist growth inhibition by temozolomide. GBM 112 and GBM 144 cells infected in vitro with HCMV resist.

Normalized weight gain of protein-sufficient and -deficient HRV-infected pigs transplanted with sufficient and deficient HIFM (sHIFM/dHIFM) and monitored.

Presentation transcript:

NK cell function of spleen MNCs (A) and NK cell frequencies in the ileum, duodenum, and spleen (B) of protein-deficient and -sufficient HIFM/HRV-infected pigs. NK cell function of spleen MNCs (A) and NK cell frequencies in the ileum, duodenum, and spleen (B) of protein-deficient and -sufficient HIFM/HRV-infected pigs. MNCs were isolated from the spleen, blood, ileum, and duodenum of piglets in the four experimental groups at PID14. (A) Spleen MNCs (piglets from all experimental groups) and carboxyfluorescein succinimidyl ester-stained K562 tumor cells were used as effector and target cells, respectively, and cocultured at set ratios to assess the cytotoxic function of NK cells (n = 10/group). Asterisks indicate statistically significant difference (two-way ANOVA; P ≤ 0.05). Error bars indicate the SEM. (B) NK cell frequencies among total MNCs were assessed by flow cytometry (n = 10/group). Asterisks indicate statistically significant differences (Kruskal-Wallis test; P ≤ 0.05). Error bars indicate the SEM. Anastasia N. Vlasova et al. mSphere 2017; doi:10.1128/mSphere.00046-17