Results from an Observational Trial: Digital Epiluminescence Microscopy Follow-Up of Atypical Nevi Increases the Sensitivity and the Chance of Success of Conventional Dermoscopy in Detecting Melanoma  Holger A. Haenssle, Ullrich Krueger, Claudia Vente, Kai-Martin Thoms, Hans P. Bertsch, Markus Zutt, Albert Rosenberger, Christine Neumann, Steffen Emmert  Journal of Investigative Dermatology  Volume 126, Issue 5, Pages 980-985 (May 2006) DOI: 10.1038/sj.jid.5700119 Copyright © 2006 The Society for Investigative Dermatology, Inc Terms and Conditions

Figure 1 Mean and 95% confidence interval of the Breslow tumor thickness for melanomas detected during follow-up by the different indicated examination techniques (P=0.591; Kruskal–Wallis test).The measures depicted in this graph were log-transformed (in contrast to the “in text” measures). Two invasive melanomas were detected by the patients' apprehension, without a suspicion by the other examination techniques (observed values shown); five invasive melanomas were detected by ELM criteria alone; nine invasive melanomas were detected by ELM criteria and also showed changes over time documented by DELM; nine invasive melanomas were exclusively detected by the comparison of DELM images with baseline images (DELM criteria alone). Journal of Investigative Dermatology 2006 126, 980-985DOI: (10.1038/sj.jid.5700119) Copyright © 2006 The Society for Investigative Dermatology, Inc Terms and Conditions