Plotted are stimulus-response curves for the flare size at feet (A) (filled symbols) and thighs (B) (open symbols) and the respective flux values (feet,

Slides:

Advertisements

Similar presentations

Diabetes hazard rates by number of visits with reported statin use.

Advertisements

Quantification of the significantly changed metabolites.

NMDA-Receptor Antagonists in Neuropathic Pain

Surface renderings of the brain activation showing significant activation in the general mixed design ANOVA for the interaction between all three factors,

Growth characteristics of strain 22A and its MDH mutant derivatives.

Obesity and type 2 diabetes forecasts.

Cumulative incidence of (A) ESRD, (B) all-cause death, (C) all-cause death without ESRD and (D) ESRD or all-cause death in patients with T1DM diagnosed.

Comparison of microbial communities in adult and children visitors and villagers. Comparison of microbial communities in adult and children visitors and.

Effect of supplementation with SeMet or SY on plasma selenium levels in adult men. Effect of supplementation with SeMet or SY on plasma selenium levels.

Changes over time in (A) waist circumference, (B) BMI, (C) ALT, (D) Matsuda index, (E) AUCglucagon, and (F) ISSI-2, comparing patients with drug-free diabetes.

Jennifer T. Thibodeau et al. JCHF 2014;2:24-31

Box- and whisker plots demonstrating the distribution of 300 μm manual trace corneal nerve fiber length (CNFL) in 39 type 1 diabetic participants. Box-

Jennifer T. Thibodeau et al. JCHF 2014;2:24-31

(A) Low-density lipoprotein-cholesterol (LDL-C) values at baseline and after treatment with anagliptin in 20 participants at 12 and 24 weeks. (A) Low-density.

Thirty-day survival curves for the rapid versus slow correction rate groups are not significantly different. Thirty-day survival curves for the rapid versus.

Change in %A1C over 5 years in response to 12-week intensive lifestyle intervention used in a real-world clinical practice. Change in %A1C over 5 years.

Relative growth of WT R2866 and the R2866ΔampG gene deletion mutant with Triton X-100. Relative growth of WT R2866 and the R2866ΔampG gene deletion mutant.

ILK knockdown increases the survival of PKD mice.

Box plots showing the relative difference in distribution of mtDNA copy number per cell between patients with ESRD and healthy control subjects frequency.

Fig. 2. Proportion of motile objects and track length

Whole-body protein kinetics in C and T2D-O during postabsorptive and clamp states. Whole-body protein kinetics in C and T2D-O during postabsorptive and.

A: Kaplan-Meier curves depicting the cumulative probability of CVE in patients with low (

NOx ASR (in mmol/day), arginine Ra (in µmol/kg × min), the fraction of arginine flux converted to NOx (%), and the insulin-mediated glucose disposal (M)

Effect of insulin on hepcidin expression in HepG2 cells.

Comparison of the protective effects of R and S isomers of LA on insulin-stimulated 2-DG uptake. Comparison of the protective effects of R and S isomers.

Top panel: AUC0–31h of M1 and glargine in the nine individual subjects (M1, open circles; glargine, filled circles) and median and 10th, 25th, 75th, and.

Leptin and amylin signaling.

PD-1 blockade results in increased expression of the chemokine receptor CXCR3. PD-1 blockade results in increased expression of the chemokine receptor.

Plasma glucose (A) and glucose specific activity (B) during euglycemic clamp experiments. Plasma glucose (A) and glucose specific activity (B) during euglycemic.

—ROC curves for each simple test compared with NCS (gold standard) plotting the sensitivity versus 1-specificity (the false-positive rate) for different.

A: Insulin-stimulated total, oxidative, and nonoxidative glucose disposal in subjects with NGT (open bars), IFG (dotted bars), IGT (striped bar), IFG/IGT.

Zn2+ and NAD(P)H content in Mafa∆panc and Mafa∆panc;Mafb+/− β-cells.

Glucose tolerance in WT and TRPM2-KO mice.

Fasting-induced lipolysis is impaired in weight-matched Ugcgf/f//CamKCreERT2 mice 3–4 weeks pi. Fasting-induced lipolysis is impaired in weight-matched.

Clustering of fat mass loss profiles in obese subjects and relation with scWAT fibrosis. Clustering of fat mass loss profiles in obese subjects and relation.

Mean fasting C-peptide levels (for all subjects [A]) and mean peak C-peptide levels (all subjects [B], adolescents [C], and adults [D])after mixed-meal.

The figure shows the mean±SD of glucose and insulin for the 2-hour OGTTs and MTTs for the 12 HP diet subjects and the 12 HC diets subjects. The figure.

Marginal means (±s.e.m.) of temperatures for four tissues in 13 king penguins while fasting in water. Marginal means (±s.e.m.) of temperatures for four.

Total plasma BCAA (A) and C3 and C5 acylcarnitine (AC) (B) concentrations in the basal state and during insulin infusion in obese subjects before and after.

Quantitation of PCR products.

Npas4 is a stress-induced factor in pancreatic β-cells.

Mice fed GP-SPI diet show improved fasting glucose and oral glucose tolerance. Mice fed GP-SPI diet show improved fasting glucose and oral glucose tolerance.

Food intake in response to central infusion of glucose (squares) or insulin (triangles) and in response to successive central infusion of insulin, insulin.

Western blot of MDA-modified proteins in FVB control, OVE26 diabetic, and catalase-protected OVE26C diabetic hearts. Western blot of MDA-modified proteins.

Percentage of weight loss over 5 years in response to 12-week intensive lifestyle intervention in a real-world clinical practice. Percentage of weight.

Spinal application of naloxone did not change population responses of superficial and deep WDR neurons to graded intracutaneous electrical stimuli in wild-type.

Treatment response patterns and effect size over time in exclusively placebo-controlled trials. Treatment response patterns and effect size over time in.

Forest plot and pooled estimates of the effect of NAFLD on the risk of incident diabetes in 16 eligible studies, stratified by length of follow-up (FU)

Interference of Kv4 in dorsal neurons (DN1s) does not significantly regulate sleep onset. Interference of Kv4 in dorsal neurons (DN1s) does not significantly.

Partial pedigrees for novel INS mutations identified in probands with MODY and young type 2 diabetes. Partial pedigrees for novel INS mutations identified.

Kaplan-Meier survival curve for CVD mortality among physically active and inactive type 2 diabetic patients stratified by baseline hs-CRP levels. Kaplan-Meier.

Effects of vinegar (□) and placebo (⧫) on plasma glucose (A–C) and insulin (D–F) responses after a standard meal in control subjects, insulin-resistant.

Percent time mouthing after water (closed symbols) and sucrose (open symbols) in infants with (circles) and without (squares) colic before taste administration.

Changes (means±posterior SDs) in HbA1c (A), fasting glucose (B), and body weight (C) by treatment condition based on missing not at random (MNAR) analyses.

A: Nerve-excitability plots for patients with DN are flatter.

Shank3 homozygous mice exibited impairment in synaptic transmission, induction, and maintenance of long-term potentiation. Shank3 homozygous mice exibited.

Noncontrast computed tomography of patient C. B

Periods of activation for the knee extensor (VL) and ankle extensor (GN) muscles with respect to foot-step contact (occurring at time zero) during stair.

FKBP1b counters the age-related decrease in hippocampal MAP2 protein expression. FKBP1b counters the age-related decrease in hippocampal MAP2 protein expression.

Immunohistochemical staining for FOXO3a of breast cancer tumor tissues

Comparison of brain temperature values in the basal ganglia and white matter according to the initial degree of encephalopathy and the presence of brain.

Profile of diastolic function parameters at rest, immediately post-exercise and into recovery. Profile of diastolic function parameters at rest, immediately.

Kaplan-Meier survival (renal event-free) curves during follow-up by tertiles of plasma copeptin. Kaplan-Meier survival (renal event-free) curves during.

Association of overall survival and PAP-specific (A, B) and PA2024-specific (C, D) CTL activity at week 26 using categorical (tertile) analysis and continuous.

Changes in the plasma N-terminal pro-brain natriuretic peptide (NT-proBNP) level from baseline to treatment titration and 3 months of therapy: full analysis.

Manhattan plot of 11,628 m/z features comparing participants who developed incident T2D versus those who did not. Manhattan plot of 11,628 m/z features.

Effects of broccoli sprouts (BS) or alfalfa sprouts (AS) on H

WM volume did not show the expected increase in volume with age in children with type 1 diabetes (●), in contrast with HC subjects (▲) who showed the (expected)

Effect of SFN on the total activity and protein expression of HDACs in JB6 P+ cells. Effect of SFN on the total activity and protein expression of HDACs.

Association of objective and self-reported PA measurements and VAT mass. Association of objective and self-reported PA measurements and VAT mass. Linear.

Presentation transcript:

Plotted are stimulus-response curves for the flare size at feet (A) (filled symbols) and thighs (B) (open symbols) and the respective flux values (feet, C, filled symbols; thighs, D, open symbols). Plotted are stimulus-response curves for the flare size at feet (A) (filled symbols) and thighs (B) (open symbols) and the respective flux values (feet, C, filled symbols; thighs, D, open symbols). A and B: Flare size was significantly reduced in SFN subjects (• and ○) and significantly enlarged in NO-Ns (▴ and ▵). Post hoc analysis of NO-N and control subjects revealed no significant differences. *Significant differences as revealed by post hoc analysis between SFN and control subjects (▪ and □) at each current intensity. C and D: Intensity of the flux within the flare did not differ between SFN and control subjects. There was, however, an increased flux in NO-Ns compared with control subjects. Post hoc analysis revealed a significant difference for 6-mA current intensity at the thigh (⋄). Heidrun H. Krämer et al. Diabetes 2004;53:769-774 ©2004 by American Diabetes Association