Summary of the relationship between environmental factors and DNA (de)methylation machinery in the regulation of adipose biology. Summary of the relationship.

Slides:

Advertisements

Similar presentations

Mutagenesis MUPGRET Workshop. Mutation Heritable change in the DNA sequence. Naturally occurring Induced.

Advertisements

Assessing functional consequences of epigenetic modifications An Data Analysis Activity for Students This teacher slide set was created by Dana Haine,

Gene Expression and Epigenetic Regulation JESSICA LAINE AND ELIZABETH MARTIN.

Modelling from Sequence to Gene Regulatory Network to Phenotype.

The Importance of Epigenetic Phenomena in Regulating Activity of the Genetic Material Sin Chan.

The Code of Life: Topic 4 Regulation of gene expression.

New insights into genome-wide change of DNA methylation and its association with gene expression in cadmium-exposed rice (Oryza sativa) Zhi.

Fabian Mohr, Konstanze Döhner, Christian Buske, Vijay P.S. Rawat

(3) Gene Expression Gene Expression (A) What is Gene Expression?

   A) B) =28 Supplementary Fig. 1. Overview of Ogg1 promotor sequence. A) Representation of the CpG-island in the Ogg1 gene region in which TF binding.

The bottom panel depicts the "breakdown" of the barriers in a cancer cell such that the transcriptionally repressive chromatin and DNA methylation all.

Fig. S1. Work flow diagram..

A Systems Toxicology-based Approach Reveals Biological Pathways Dysregulated by Prenatal Arsenic Exposure Jessica E. Laine, MS, Rebecca C. Fry, PhD

Covalent Modification of DNA Regulates Memory Formation

Volume 145, Issue 2, Pages (August 2013)

Can you think of any characteristics or traits you may have that could be affected by the environment?

Biomathematical Modeling: The Deletion of HMO1 and its Effect on Cold Shock Reaction in S. cerevisiae Lauren Magee & Lucia Ramirez Department of Mathematics.

Adding & Subtracting Integers

RNA processing and transport RNA degradation Translation

COMBINING LIKE TERMS & DISTRIBUTIVE PROPERTY

Significance Table from Anova Test

DNA, protein synthesis, gene expression & mutations

Demethylation of an NF-κB enhancer element orchestrates iNOS induction in osteoarthritis and is associated with altered chondrocyte cell cycle M.C. de.

Meiosis: Organizing Microtubule Organizers

The Genetic Basis and Expanding Role of Molecular Analysis in the Diagnosis, Prognosis, and Therapeutic Design for Myelodysplastic Syndromes Grant E.

Cyclin transcription: Timing is everything

High-Resolution Genetic Maps Identify Multiple Type 2 Diabetes Loci at Regulatory Hotspots in African Americans and Europeans Winston Lau, Toby Andrew,

Hakan Bagci, Amanda G. Fisher Cell Stem Cell

COMBINING LIKE TERMS.

Mutations Section 6.2.

Effect of oocyte vitrification on deoxyribonucleic acid methylation of H19, Peg3, and Snrpn differentially methylated regions in mouse blastocysts Ke-Ren.

What number is the arrow pointing at?

Allele-Specific Methylome and Transcriptome Analysis Reveals Widespread Imprinting in the Human Placenta Hirotaka Hamada, Hiroaki Okae, Hidehiro Toh,

Epigenetic regulation of miR-193b in liposarcomagenesis.

(Within-Strain ANOVA)

Molecular cloning of pms916 salt hypersensitive T-DNA mutant.

12.4 Mutations Kinds of Mutations Significance of Mutations.

How do external factors change an organism's genes to affect their offspring? Lecture 2: Environmental factors, such as radiation, can cause mutations.

Mira Jeong, Margaret A. Goodell Experimental Hematology

Imprinting at the SMPD1 Locus: Implications for Acid Sphingomyelinase–Deficient Niemann-Pick Disease Calogera M. Simonaro, Jae-Ho Park, Efrat Eliyahu,

Learn to combine like terms in an expression.

Revisiting Global Gene Expression Analysis

DNA methylation in hematopoietic development and disease

Transcriptionally regulated genes in Δsaci_ptp and Δsaci_pp2a as compared with the strain MW001. Transcriptionally regulated genes in Δsaci_ptp and Δsaci_pp2a.

Bar plot representation of the transcriptomic changes in Δsaci_ptp and Δsaci_pp2a. Bar plot representation of the transcriptomic changes in Δsaci_ptp and.

Role of histone modification in transcription. Development imprinting.

Elanor N. Wainwright, Paola Scaffidi Trends in Cancer

Nucleic Acid Modifications in Regulation of Gene Expression

Basic concepts of epigenetics

Fabian Mohr, Konstanze Döhner, Christian Buske, Vijay P.S. Rawat

Volume 46, Issue 2, Pages (April 2012)

Supplementary Materials DNMT1-shRNA’ DNMT1-shRNA control DNMT1 DNMT3a

Figure 1. Kidney-Specific Cre/loxP Recombination.

Genomic imprinting Current Biology

Stéphan Hardivillé, Gerald W. Hart Cell Metabolism

Fig. 1. Generation of WNK3 knockout mice

Nature of Biology 1 Chapter 15 pg

Fig. 5. Vitamin B12 supplementation in the host altered the transcriptome of P. acnes in the skin microbiota. Vitamin B12 supplementation in the host altered.

Copyright Pearson Prentice Hall

Transcriptional control: Imprinting insulation

A, high-resolution methylation analysis of ZNF545 promoter by BGS in representative carcinoma cell lines. A, high-resolution methylation analysis of ZNF545.

Microarray analysis of global gene expression profiles of PC-3 and derivative cell lines. Microarray analysis of global gene expression profiles of PC-3.

Methylation targets of TET1 in vitro.

Identification of putative TET1 targets in TNBC

Epigenetic mechanisms and the development of asthma

Presentation transcript:

Summary of the relationship between environmental factors and DNA (de)methylation machinery in the regulation of adipose biology. Summary of the relationship between environmental factors and DNA (de)methylation machinery in the regulation of adipose biology. Various perturbations from environmental cues affect the expression or activity of DNMTs and TETs, which alters the DNA methylation profile of specific target genes with concordant changes in gene expression and phenotypic changes in adipose biology. The dotted line is used to depict relationships with weaker evidence. Small arrow inserts indicate the direction of change in DNA methylation at affected genes. Plus and minus signs indicate the direction of gene expression change. Xiang Ma, and Sona Kang Diabetes 2019;68:871-878 ©2019 by American Diabetes Association