Evaluation of rotation thrombelastography for the diagnosis of hyperfibrinolysis in trauma patients A. Levrat, A. Gros, L. Rugeri, K. Inaba, B. Floccard,

Slides:

Advertisements

Similar presentations

Monitoring and Treatment of Coagulation Disorders in End-Stage Liver Disease Visc Med 2016;32: DOI: / Fig. 1. On the left side,

Advertisements

From: First-line Therapy with Coagulation Factor Concentrates Combined with Point-of-Care Coagulation Testing Is Associated with Decreased Allogeneic Blood.

From: Evaluation of a Novel Transfusion Algorithm Employing Point-of-care Coagulation Assays in Cardiac Surgery:A Retrospective Cohort Study with Interrupted.

Randomized evaluation of fibrinogen vs placebo in complex cardiovascular surgery (REPLACE): a double-blind phase III study of haemostatic therapy N.

C. Solomon, R.E. Collis, P.W. Collins British Journal of Anaesthesia

Plasma concentrations and sedation scores after nebulized and intranasal midazolam in healthy volunteers A.S.M. McCormick, V.L. Thomas, D. Berry, P.W.

Point-of-care viscoelastic testing improves the outcome of pregnancies complicated by severe postpartum hemorrhage Denis Snegovskikh, M.D., Dmitri Souza,

Preventing surgical deaths: critical care and intensive care outreach services in the postoperative period D.R. Goldhill British Journal of Anaesthesia

Haemodilution-induced profibrinolytic state is mitigated by fresh-frozen plasma: implications for early haemostatic intervention in massive haemorrhage

L. A. Tafur, P. Taura, A. Blasi, J. Beltran, G. Martinez-Palli, J

Reversal by the specific antidote, idarucizumab, of elevated dabigatran exposure in a patient with rectal perforation and paralytic ileus C. Thorborg,

G Weiss, S Lison, M Spannagl, B Heindl British Journal of Anaesthesia

Why is the surgical high-risk patient still at risk?

Supplemental oxygen and surgical site infection: getting to the truth

Rotation thromboelastometry detects thrombocytopenia and hypofibrinogenaemia during orthotopic liver transplantation S. Roullet, J. Pillot, G. Freyburger,

Parkinson's disease and anaesthesia

International normalized ratio and prothrombin time values before the removal of a lumbar plexus catheter in patients receiving warfarin after total hip.

Pleth variability index to monitor the respiratory variations in the pulse oximeter plethysmographic waveform amplitude and predict fluid responsiveness.

Effects of colloid and crystalloid solutions on endogenous activation of fibrinolysis and resistance of polymerized fibrin to recombinant tissue plasminogen.

Does prior administration of enoxaparin influence the effects of levobupivacaine on blood clotting? Assessment using the Thrombelastograph® S.A. Leonard,

D. Fries, A. Krismer, A. Klingler, W. Streif, G. Klima, V. Wenzel, T

Perioperative treatment algorithm for bleeding burn patients reduces allogeneic blood product requirements E. Schaden, O. Kimberger, P. Kraincuk, D.M.

High-frequency oscillatory ventilation and an interventional lung assist device to treat hypoxaemia and hypercapnia David M. , Heinrichs W. British.

Retrospective analysis of the incidence of epidural haematoma in patients with epidural catheters and abnormal coagulation parameters P. Gulur, B. Tsui,

Perioperative factor concentrate therapy

Five-minute parameter of thromboelastometry is sufficient to detect thrombocytopenia and hypofibrinogenaemia in patients undergoing liver transplantation

Evaluation of a single preoperative dose of pregabalin for attenuation of postoperative pain after laparoscopic cholecystectomy A. Agarwal, S. Gautam,

M Ranucci, E Baryshnikova British Journal of Anaesthesia

I. Merino, X. Borrat, J. Balust, S. Delgado, A. M. Lacy, J. Vidal, G

Premedication with pregabalin 75 or 150 mg with ibuprofen to control pain after day- case gynaecological laparoscopic surgery R. Jokela, J. Ahonen, M.

Efficacy of intravenous magnesium in neuropathic pain

Update on massive transfusion

Psychology of pain British Journal of Anaesthesia

K.J. Chin British Journal of Anaesthesia

Cardiovascular and arousal responses to laryngoscopy and tracheal intubation in patients with complete spinal cord injury K.Y. Yoo, C.W. Jeong, S.J.

Comparative study of topical anaesthesia with lidocaine 2% vs levobupivacaine 0.75% in cataract surgery S.A. Fernández, E. Dios, J.C. Diz British Journal.

Use of an anaesthesia workstation barrier device to decrease contamination in a simulated operating room S Hunter, D Katz, A Goldberg, H.-M. Lin, R Pasricha,

V. Uppal, G. Fletcher, J. Kinsella British Journal of Anaesthesia

H. Tønnesen, P.R. Nielsen, J.B. Lauritzen, A.M. Møller

Perioperative monitoring of platelet function in paediatric cardiac surgery by thromboelastometry, or platelet aggregometry?† B.S. Romlin, F Söderlund,

Role of fibrinogen in trauma-induced coagulopathy

Magnesium sulphate as a technique of hypotensive anaesthesia

Physiological effects of hyperchloraemia and acidosis

Thromboelastometry (ROTEM®) in children: age-related reference ranges and correlations with standard coagulation tests E Oswald, B Stalzer, E Heitz,

The output of two sevoflurane vaporizers in the presence of helium

Anaesthesia for awake craniotomy—evolution of a technique that facilitates awake neurological testing A. Sarang, J. Dinsmore British Journal of Anaesthesia

Effects of tracheal tube orientation on the success of intubation through an intubating laryngeal mask airway: study in Mallampati class 3 or 4 patients

Effects of protamine and heparin can be detected and easily differentiated by modified thrombelastography (Rotem®): an in vitro study M Mittermayr, J.

Factors associated with prophylactic plasma transfusion before vascular catheterization in non-bleeding critically ill adults with prolonged prothrombin.

GlideScope® video laryngoscope: a randomized clinical trial in 203 paediatric patients† J.-T. Kim, H.-S. Na, J.-Y. Bae, D.-W. Kim, H.-S. Kim, C.S. Kim,

High-dose tinzaparin in pregnancy and the need for urgent delivery

Measurement of surgical stress in anaesthetized children

Fibrinogen supplementation ex vivo increasesclot firmness comparable to platelet transfusion in thrombocytopenia† B. Schenk, A.K. Lindner, B. Treichl,

Early thromboelastometry variables predict maximum clot firmness in children undergoing cardiac and non-cardiac surgery A. Perez-Ferrer, J. Vicente-Sanchez,

G.J. Mar, M.J. Barrington, B.R. McGuirk British Journal of Anaesthesia

Prevalence and impact of abnormal ROTEM® assays in severe blunt trauma: results of the ‘Diagnosis and Treatment of Trauma-Induced Coagulopathy (DIA-TRE-TIC)

Activated thrombelastogram in neonates and infants with complex congenital heart disease in comparison with healthy children B. Haizinger, H. Gombotz,

Parecoxib for analgesia after craniotomy

G.B. Drummond, B. Lafferty British Journal of Anaesthesia

Diagnosis of vertebral canal haematoma by myelography and spiral computer tomography in a patient with an implantable cardioverter-defibrillator contraindicating.

Phasic voltage ECG variation during laparoscopy

Tension enterothorax British Journal of Anaesthesia

Fibrinogen concentrate substitution therapy in patients with massive haemorrhage and low plasma fibrinogen concentrations C. Fenger-Eriksen, M. Lindberg-Larsen,

Development and validation of a preoperative scoring system to predict 30 day mortality in patients undergoing hip fracture surgery M.J. Maxwell, C.G.

Inter-hemispheric cerebral oxygen saturation differences during thoracic surgery in lateral head positioning† T.M. Hemmerling, R. Kazan, D. Bracco British.

C. Verghese, B. Ramaswamy British Journal of Anaesthesia

I.V. ropivacaine compared with lidocaine for the treatment of tinnitus

M. J. Sheen, S. -T. Ho, C. -H. Lee, Y. -C. Tsung, F. -L. Chang, S. -T

Closed-loop control of propofol anaesthesia using bispectral index™: performance assessment in patients receiving computer-controlled propofol and manually.

Thromboelastometry-guided administration of fibrinogen concentrate for the treatment of excessive intraoperative bleeding in thoracoabdominal aortic aneurysm.

Presentation transcript:

Evaluation of rotation thrombelastography for the diagnosis of hyperfibrinolysis in trauma patients A. Levrat, A. Gros, L. Rugeri, K. Inaba, B. Floccard, C. Negrier, J.-S. David British Journal of Anaesthesia Volume 100, Issue 6, Pages 792-797 (June 2008) DOI: 10.1093/bja/aen083 Copyright © 2008 British Journal of Anaesthesia Terms and Conditions

Fig 1 (a) Normal ROTEM® tracing with reference ranges in brackets. CT, clotting time; CFT, clotting formation time; CA, clot amplitude at 10 or 15 min; MCF, maximum clot firmness; CLI, clot lysis index at 30 or 60 min. (b) ROTEM® tracing depicting severe coagulation abnormalities (decrease of MCF and CA15 in EXTEM, absence of clot in FIBTEM) with hyperfibrinolysis (MCF-EXTEM <18 mm and ΔMCF >9%). Severe coagulation abnormalities were confirmed by standard coagulations parameters (INR: 4.7, fibrinogen: 0.4 g litre−1) and hyperfibrinolysis by an ELT score of 2. (c) ROTEM® tracing depicting severe coagulation abnormalities (decrease of MCF and CA15 in EXTEM, the absence of clot in FIBTEM) but without evidence of hyperfibrinolysis (MCF-EXTEM >18 mm and ΔMCF <7%). Severe coagulation abnormalities were confirmed by standard coagulation parameters (INR: 3.9, fibrinogen: 0.5 g litre−1) and the absence of hyperfibrinolysis by an ELT score of 0. (d) ROTEM® tracing depicting severe coagulation abnormalities with virtually no coagulation process on ROTEM® (no clot on any ROTEM® channel testing). Severe coagulation abnormalities were confirmed by standard coagulation parameters (INR: 10, fibrinogen: 0 g litre−1) and hyperfibrinolysis by an ELT score of 4. British Journal of Anaesthesia 2008 100, 792-797DOI: (10.1093/bja/aen083) Copyright © 2008 British Journal of Anaesthesia Terms and Conditions