Association, prevalence, and clearance of human papillomavirus and antisperm antibodies in infected semen samples from infertile patients Andrea Garolla,

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Presentation transcript:

Association, prevalence, and clearance of human papillomavirus and antisperm antibodies in infected semen samples from infertile patients Andrea Garolla, M.D., Damiano Pizzol, M.D., Alessandro Bertoldo, B.Sc., Luca De Toni, B.Sc., Luisa Barzon, M.D., Carlo Foresta, Ph.D. Fertility and Sterility Volume 99, Issue 1, Pages 125-131.e2 (January 2013) DOI: 10.1016/j.fertnstert.2012.09.006 Copyright © 2013 American Society for Reproductive Medicine Terms and Conditions

Figure 1 Confocal microscopic analysis for HPV 16-L1 and immunoglobulins. (A) Costaining of IgA and IgG with HPV proteins in ASA-positive infected samples. (B) Absence of immunoglobulins staining in ASA-negative infected samples. Fertility and Sterility 2013 99, 125-131.e2DOI: (10.1016/j.fertnstert.2012.09.006) Copyright © 2013 American Society for Reproductive Medicine Terms and Conditions

Figure 2 Follow-up of 61 infertile patients with HPV sperm infection. Chart shows the prevalence and clearance of both sperm infection and ASAs at 0, 12, and 24 months. Fertility and Sterility 2013 99, 125-131.e2DOI: (10.1016/j.fertnstert.2012.09.006) Copyright © 2013 American Society for Reproductive Medicine Terms and Conditions

Supplemental Figure 1 Example of FISH analysis for HPV performed on semen samples from infertile patients. (A) Noninfected sperm samples; (B) infected sperm. Fertility and Sterility 2013 99, 125-131.e2DOI: (10.1016/j.fertnstert.2012.09.006) Copyright © 2013 American Society for Reproductive Medicine Terms and Conditions

Supplemental Figure 2 Picture of positive spermMar test obtained from an infected semen sample. Fertility and Sterility 2013 99, 125-131.e2DOI: (10.1016/j.fertnstert.2012.09.006) Copyright © 2013 American Society for Reproductive Medicine Terms and Conditions