Propofol-based anaesthesia versus sevoflurane-based anaesthesia for living donor kidney transplantation: results of the VAPOR-1 randomized controlled.

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Propofol-based anaesthesia versus sevoflurane-based anaesthesia for living donor kidney transplantation: results of the VAPOR-1 randomized controlled trial G.J. Nieuwenhuijs-Moeke, V.B. Nieuwenhuijs, M.A.J. Seelen, S.P. Berger, M.C. van den Heuvel, J.G.M. Burgerhof, P.J. Ottens, R.J. Ploeg, H.G.D. Leuvenink, M.M.R.F. Struys British Journal of Anaesthesia Volume 118, Issue 5, Pages 720-732 (May 2017) DOI: 10.1093/bja/aex057 Copyright © 2017 The Author(s) Terms and Conditions

Fig 1 Consort diagram. British Journal of Anaesthesia 2017 118, 720-732DOI: (10.1093/bja/aex057) Copyright © 2017 The Author(s) Terms and Conditions

Fig 2 Urinary concentrations of renal injury markers. Time points are as follows: first urine produced upon reperfusion, 2 h post-transplantation, day 1, 2, 6, and 9. Values are corrected for creatinine and displayed per group for every individual patient. Groups are as follows: PROP (donor and recipient propofol), SEVO (donor and recipient sevoflurane), and PROSE (donor propofol and recipient sevoflurane). H-FABP, heart-type fatty acid binding protein; KIM-1, kidney injury molecule-1; NAG, N-acetyl-β-d-glucosaminidase. Differences were tested with the Kruskal–Wallis test and post hoc with the Bonferroni test. British Journal of Anaesthesia 2017 118, 720-732DOI: (10.1093/bja/aex057) Copyright © 2017 The Author(s) Terms and Conditions

Fig 3 Kaplan–Meier curves of the occurrence of acute rejection during 2 yr follow-up. The rejection-free fraction is displayed on the y-axis. Groups are as follows: PROP (donor and recipient propofol), SEVO (donor and recipient sevoflurane), and PROSE (donor propofol and recipient sevoflurane). Acute rejection episodes were tested with the log-rank test. British Journal of Anaesthesia 2017 118, 720-732DOI: (10.1093/bja/aex057) Copyright © 2017 The Author(s) Terms and Conditions