Volume 87, Issue 3, Pages (March 2015)

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Volume 87, Issue 3, Pages 575-583 (March 2015) The mortality risk with graft function has decreased among children receiving a first kidney transplant in the United States Benjamin L. Laskin, Mark M. Mitsnefes, Mourad Dahhou, Xun Zhang, Bethany J. Foster Kidney International Volume 87, Issue 3, Pages 575-583 (March 2015) DOI: 10.1038/ki.2014.342 Copyright © 2015 International Society of Nephrology Terms and Conditions

Figure 1 Kaplan–Meier estimate of survival for children receiving their first kidney transplant in the United States in successive time periods. The number of individuals still under observation at 1, 2, 5, 10, 15, and 20 years after first kidney transplant is indicated in the table below the curves. The log-rank P-value for comparisons between time periods was <0.0001. Kidney International 2015 87, 575-583DOI: (10.1038/ki.2014.342) Copyright © 2015 International Society of Nephrology Terms and Conditions

Figure 1 Kaplan–Meier estimate of survival for children receiving their first kidney transplant in the United States in successive time periods. The number of individuals still under observation at 1, 2, 5, 10, 15, and 20 years after first kidney transplant is indicated in the table below the curves. The log-rank P-value for comparisons between time periods was <0.0001. Kidney International 2015 87, 575-583DOI: (10.1038/ki.2014.342) Copyright © 2015 International Society of Nephrology Terms and Conditions

Kidney International 2015 87, 575-583DOI: (10.1038/ki.2014.342) Copyright © 2015 International Society of Nephrology Terms and Conditions

Figure 2 Adjusted covariate hazard ratios for all-cause mortality after kidney transplant. The hazard ratios (HRs) for each covariate (circles) and their 95% confidence intervals (CIs) (vertical bars) are plotted on a logarithmic scale. Models focusing on observation with graft function are shown by the dashed horizontal lines, with the HR (95% CI) displayed in italics on the right side of the figure. Models focusing on all observation time after first transplant are shown by the solid horizontal lines, with the HR (95% CI) displayed in bold on the right side of the figure. *Indicates a statistically significant HR. Models were adjusted for recipient age, recipient age squared, donor (living vs. deceased), gender, primary renal disease, socioeconomic status quartile, duration of dialysis before first transplant, race, insurance coverage, and number of comorbidities. Model focusing on observation with graft function was also adjusted for renal replacement therapy modality (graft function vs. dialysis after graft failure—a time-dependent variable). Kidney International 2015 87, 575-583DOI: (10.1038/ki.2014.342) Copyright © 2015 International Society of Nephrology Terms and Conditions