Volume 75, Issue 5, Pages (March 2009)

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Presentation transcript:

Volume 75, Issue 5, Pages 453-454 (March 2009) Journal Club Kidney International Volume 75, Issue 5, Pages 453-454 (March 2009) DOI: 10.1038/ki.2008.696 Copyright © 2009 International Society of Nephrology Terms and Conditions

Renal fibrosis induced in Pax8-rtTA/TetO–TGF-β1 double-transgenic mice Renal fibrosis induced in Pax8-rtTA/TetO–TGF-β1 double-transgenic mice. Pax8-rtTA/TetO–TGF-β1 double-transgenic mice were treated with doxycycline, and overexpression of TGF-β1 led to massive extracellular matrix accumulation and prominent renal fibrosis, as indicated here by collagen I immunohistochemistry in non-induced (left) and induced (right) mice. Kidney International 2009 75, 453-454DOI: (10.1038/ki.2008.696) Copyright © 2009 International Society of Nephrology Terms and Conditions

In situ hybridization analysis of Wnt7b expression in the mouse kidney. Kidney International 2009 75, 453-454DOI: (10.1038/ki.2008.696) Copyright © 2009 International Society of Nephrology Terms and Conditions

Neu5Gc-dependent binding of SubAB to human tissues Neu5Gc-dependent binding of SubAB to human tissues. Specific binding of SubAB to human kidney sections, particularly the glomerular endothelium, was observed, but this was not seen for SubABA12 mutant toxin. Kidney International 2009 75, 453-454DOI: (10.1038/ki.2008.696) Copyright © 2009 International Society of Nephrology Terms and Conditions