A previously healthy 44-year-old woman presented with subacute psychiatric disturbance with no fever or seizures. A previously healthy 44-year-old woman.

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Presentation transcript:

A previously healthy 44-year-old woman presented with subacute psychiatric disturbance with no fever or seizures. A previously healthy 44-year-old woman presented with subacute psychiatric disturbance with no fever or seizures. A, Bilateral and asymmetric hyperintensity was observed on an axial FLAIR image in the enlarged amygdalae and hippocampi (asterisks), predominantly on the left side. B, A faint ill-defined enhancement of the left hippocampus was documented on an axial T1 postcontrast image (arrowheads). Autoimmune encephalitis was considered, and the presence of anti–N-methyl-D-aspartate receptor autoantibodies was confirmed. C and D, Imaging follow-up revealed signal abnormalities and atrophy on FLAIR that involved the hippocampus, amygdala, parahippocampal gyrus, and left insula (arrowheads), compatible with severe sequelae. A.J. da Rocha et al. AJNR Am J Neuroradiol 2015;36:2196-2205 ©2015 by American Society of Neuroradiology