Osmotic nephrosis in a renal transplant recipient

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Presentation transcript:

Osmotic nephrosis in a renal transplant recipient Z. Ebcioglu, D.J. Cohen, R.J. Crew, M.A. Hardy, L.E. Ratner, V.D. D'Agati, G.S. Markowitz Kidney International Volume 70, Issue 10, Pages 1873-1876 (November 2006) DOI: 10.1038/sj.ki.5001737 Copyright © 2006 International Society of Nephrology Terms and Conditions

Figure 1 Osmotic nephrosis is characterized by marked swelling of proximal tubular epithelia that contain abundant clear cytoplasmic vacuoles. Compared to the isometric tubular vacuolization seen with calcineurin inhibitor toxicity, the cells appear more swollen and the vacuoles are larger, more abundant, and more diffusely distributed. (Hematoxylin and eosin original magnification, × 400.) Kidney International 2006 70, 1873-1876DOI: (10.1038/sj.ki.5001737) Copyright © 2006 International Society of Nephrology Terms and Conditions