Early consumption of peanuts in infancy is associated with a low prevalence of peanut allergy George Du Toit, FRCPCH, Yitzhak Katz, MD, PhD, Peter Sasieni,

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Presentation transcript:

Early consumption of peanuts in infancy is associated with a low prevalence of peanut allergy George Du Toit, FRCPCH, Yitzhak Katz, MD, PhD, Peter Sasieni, PhD, David Mesher, MSc, Soheila J. Maleki, PhD, Helen R. Fisher, BSc, Adam T. Fox, FRCPCH, Victor Turcanu, MD, PhD, Tal Amir, Galia Zadik-Mnuhin, MD, Adi Cohen, MD, Irit Livne, MD, Gideon Lack, FRCPCH Journal of Allergy and Clinical Immunology Volume 122, Issue 5, Pages 984-991 (November 2008) DOI: 10.1016/j.jaci.2008.08.039 Copyright © 2008 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 1 Kaplan-Meier estimates for age at which foods are introduced and duration of breast-feeding and exclusive breast-feeding according to country. ∗The y-axis represents proportions who have consumed food by age (in months). ∗∗The y-axis represents the proportion still breast-feeding/exclusively breast-feeding at various ages (in months). P values are derived by using the log-rank test. Journal of Allergy and Clinical Immunology 2008 122, 984-991DOI: (10.1016/j.jaci.2008.08.039) Copyright © 2008 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 2 Major allergen content and IgE binding of peanut foods in the UK and Israel. Slot-blot analysis of Israeli peanut snacks and 2 commonly consumed peanut butters from the UK is shown. Serial dilutions of peanut protein from each food can be seen from the highest dilution (lane 1) through the lowest dilution (lane 6). Each of 4 membranes was probed with either anti-Ara h 1 (Anti-A1), anti-Ara h 2 (Anti-A2), or anti-Ara h 3 (Anti-A3) or a pool of 9 patient sera IgE from individuals with PA. Journal of Allergy and Clinical Immunology 2008 122, 984-991DOI: (10.1016/j.jaci.2008.08.039) Copyright © 2008 American Academy of Allergy, Asthma & Immunology Terms and Conditions