Joseph J. Piotrowski, MD, Glenn C. Hunter, MD, Cleamond D

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Presentation transcript:

Lipid peroxidation: A possible factor in late graft failure of coronary artery bypass grafts Joseph J. Piotrowski, MD, Glenn C. Hunter, MD, Cleamond D. Eskelson, MD, Gulshan K. Sethi, MD, Jack C. Copeland, MD, Kenneth E. McIntyre, MD, Earl D. Cottrell, MD, Maria L. Aguirre, MD, Victor M. Bernhard, MD Journal of Vascular Surgery Volume 13, Issue 5, Pages 652-658 (May 1991) DOI: 10.1016/0741-5214(91)90349-Y Copyright © 1991 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 1 Explanted vein graft demonstrates marked thickening of the vessel wall. The lumen is occluded by thrombus containing cholesterol clefts and lipid laden macrophages. (Hematoxylin = eosin stain; original magnification × 27.) Journal of Vascular Surgery 1991 13, 652-658DOI: (10.1016/0741-5214(91)90349-Y) Copyright © 1991 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 2 A high-power view of a section of the vein graft shown in Fig. 1 demonstrates cholesterol clefts, foam cells, and occasional lymphocytes. Thrombus is present on the luminal surface. (Hematoxylin = eosin stain; original magnification × 472.) Journal of Vascular Surgery 1991 13, 652-658DOI: (10.1016/0741-5214(91)90349-Y) Copyright © 1991 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions