A B C D E F Supplementary Fig. 3. Gating strategy for ES2 ALDHhi tumor initiating cells (TIC). Cells were treated with the specific aldehyde dehydrogenase.

Slides:



Advertisements
Similar presentations
Fig. 4-1, p Fig. 4-2, p. 109 Fig. 4-3, p. 110.
Advertisements

P.464. Table 13-1, p.465 Fig. 13-1, p.466 Fig. 13-2, p.467.
Fig. 11-1, p p. 360 Fig. 11-2, p. 361 Fig. 11-3, p. 361.
Table 6-1, p Fig. 6-1, p. 162 p. 163 Fig. 6-2, p. 164.
P Fig. 6-1, p. 193 Fig. 6-2, p. 193 Fig. 6-3, p. 195.
Figure 1.1 The observer in the truck sees the ball move in a vertical path when thrown upward. (b) The Earth observer views the path of the ball as a parabola.
Investigating the effects of human aldehyde dehydrogenase on vaccinia virus replication in breast cancer stem cells Mazin Elsarrag BNFO /4/2014.
SIRTs inhibitor: Sirtinol Supplementary Figure S3A Supplementary Figure S3 Sirtinol but not EX527 or PDF-170 significantly enhances ithe cytotoxic and.
CD44 PD-L1 FSC Human/Mouse Stromal Markers FSC DAPI FSC SSC FSC-W FSC-H SSC-W SSC-H Live cells Tumor cells CD44 - CD44 + Supplementary Figure S1. Gating.
CD8 CD4 IgM B220 ThymusA. C.BM D. LN CD4 CD8 CD43 B220 IgM Spleen counts B220 IgD E. F. Kim et al._Fig. S1. PIDD +/+PIDD -/- Spleen CD44 CD25 Gated on.
Differential drug responses of circulating tumor cells within patient blood Andrew D. Hughes, Jocelyn R. Marshall, Eric Keller, John D. Powderly, Bryan.
A B Pax8 CK7 CA125 HE4 HE xenograft tumor primary #20 bright phase HE
 (1) recombinant DNA technology or DNA cloning,  (2) reproductive cloning  (3) therapeutic cloning.
Generation of Novel Thyroid Cancer Stem-Like Cell Clones
Treatment with ipilimumab
Supplementary figures
advanced lung adenocarcinoma subtype
Supplementary Figures S1 to S36
Expression of stem cell markers in oral cavity and oropharynx squamous cell carcinoma  Flávia Paiva Prudente de Moraes, MD, Silvia Vanessa Lourenço, PhD,
A B C D Rao et al., 2012; Supplementary Figure S1 p = 0.03 p = NS
Treatment with ipilimumab
A B C MDA-MB-231 OHT: h FOXM1 PLK CDC25b ERα Tubulin
DNA damage foci in irradiated cells.
Inhibitor of MAP kinase activation blocks colon cancer growth
Volume 4, Issue 3, Pages (April 2018)
Human articular chondrocytes with higher aldehyde dehydrogenase activity have stronger expression of COL2A1 and SOX9  A. Unguryte, E. Bernotiene, E. Bagdonas,
European Urology Oncology
Identification of a subset of human natural killer cells expressing high levels of programmed death 1: A phenotypic and functional characterization  Silvia.
Immunotherapy.
A B C D E F Supplementary Fig. 1. Gating strategy for CD44+CD133+CD24+ B16 tumor initiating cells (TIC). Cells were gated on CD44. CD44 positive cells.
A B C D E F Supplementary Fig. 2. Gating strategy for CD44+CD24+ ID8agg tumor initiating cells (TIC). Cells were gated on CD44. CD44 positive cells were.
Volume 12, Issue 12, Pages (September 2015)
IHC staining of FFPE esophageal tissues in tissue microarrays (×20).
Days after cell inoculation Days after cell inoculation
Days after cell inoculation Days after cell inoculation
Nat. Rev. Nephrol. doi: /nrneph
Supplementary figure1. CK7 CK20 CDX2 DPEP1 Cut off value: 85%
COX-2–PGE2 signaling is required for MSC-induced increase in ALDHhigh CSC-enriched population and tumor initiation. COX-2–PGE2 signaling is required for.
Down-Regulation of SOX2 Underlies the Inhibitory Effects of the Triphenylmethane Gentian Violet on Melanoma Cell Self-Renewal and Survival  Silvia Pietrobono,
Clinical courses of patients.
Volume 1, Issue 5, Pages (November 2007)
Refer to word document for this table
Volume 141, Issue 5, Pages (November 2011)
Anti-tumor effect of anti-PD-1 antibody against SCC3 tumor
Volume 25, Issue 4, Pages (April 2017)
NEGATIVE VOLTAGE POSITIVE.
PD-1–PD-L1 axis is highly expressed and is not IFNγ-dependent in a subcutaneous murine model of PDA. A, experimental design for establishment of subcutaneous.
Supplementary Figure S1
Supplementary Figure 1 SK-N-SH Vehicle GW9662 Number of cells
Fig. 7. SCF and IGF-1 accelerate fetal spleen erythropoiesis in vivo.
C A B * * * * HCC1954 HCC1569 Supplementary-Figure S5 Tumor cells sc.
Highly related T9 and T3 sarcoma cells show distinct tumor growth patterns but similar PD-L1 expression kinetics in vivo. Highly related T9 and T3 sarcoma.
Socs1 KD tumors exhibit a more T-cell–inflamed phenotype and increased T-cell activation. Socs1 KD tumors exhibit a more T-cell–inflamed phenotype and.
PD1 targeting alters the recruitment of immune cells to MC38 CRC tumors. PD1 targeting alters the recruitment of immune cells to MC38 CRC tumors. MC38.
Fig. 4. Activations of FAK, Erk, and Akt pathways by OPNpt20
Fig. 3. On pathology examination, (a) low-power field (× 40) and (b) high-power field (× 200) images of the tumor reveal biphasic proliferation and a multinodular.
Induction of cytotoxic activity in humanized SCC3 tumor-bearing mice treated with anti-PD-1 antibody. Induction of cytotoxic activity in humanized SCC3.
Kaplan–Meier curves for PFS and OS (for patients treated with anti-PD-1/PD-L1 monotherapy). Kaplan–Meier curves for PFS and OS (for patients treated with.
Fig. 2. Pathologic findings of Case 1
Convergent expansion in less predominant B-lineage clones.
Targeting GAPLINC decreased CD44 expression and tumor growth in vivo.
Moderate-affinity vaccine antigens elicited greatest antitumor response. Moderate-affinity vaccine antigens elicited greatest antitumor response. Wild-type.
MTOR kinase inhibition–induced reactivation of AKT substrates is HER2 and PI3K dependent. mTOR kinase inhibition–induced reactivation of AKT substrates.
Venn diagram showing the overlap of PD-L1 overexpression, MSI-NGS–high, and TML-high in all gastrointestinal tumors, with all three markers tested (N =
Supplementary Table 2. Antibodies and conditions used for the IHC studies.
IL2Cx alone or in combination with anti–CTLA-4 increases the CD8/Treg ratio in the tumor. IL2Cx alone or in combination with anti–CTLA-4 increases the.
Phenotypic diversity of less predominant B-lineage clones.
Quantitative PCR (A) and Western blot (B) analyses for expression of CD133 and ALDH isoforms in CD133+ and CD133− cells sorted from HCC cell lines PLC8024.
Technology schematic for phenotypic tracking of single molecularly defined B-lineage clones. Technology schematic for phenotypic tracking of single molecularly.
IHC staining of FFPE esophageal tissues in tissue microarrays (×20).
Presentation transcript:

A B C D E F Supplementary Fig. 3. Gating strategy for ES2 ALDHhi tumor initiating cells (TIC). Cells were treated with the specific aldehyde dehydrogenase (ALDH) inhibitor diethylaminobenzaldehyde (DEAB), as a negative control to set the gate for ALDHhi cells, considered as TIC. (A) Negative control ES2 control. (B) ALDHhi ES2 control cells. (C) Negative control, ES2 PD-L1lo clone 1. (D) ALDHhi ES2 PD-L1lo clone 1 cells. (E) Negative control, ES2 PD-L1lo clone 2. (F) ALDHhi ES2 PD-L1lo clone 2 cells.