Effects of helium–neon laser on the mucopolysaccharide induction in experimental osteoarthritic cartilage  Y.-S. Lin, M.Sc, Dr M.-H. Huang, M.D., Ph.D., Dr C.-Y. Chai, M.D., Ph.D.  Osteoarthritis and Cartilage  Volume 14, Issue 4, Pages 377-383 (April 2006) DOI: 10.1016/j.joca.2005.10.010 Copyright © 2005 OsteoArthritis Research Society International Terms and Conditions

Fig. 1 The mucopolysaccharide distribution in articular cartilage of normal (A), moderate arthritis group II before laser treatment (B), after laser treatment IIs (C), and control rats IIc (D). t: Tangential layer; i: Intermediate layer; and r: Radiating layer of articular cartilage. Osteoarthritis and Cartilage 2006 14, 377-383DOI: (10.1016/j.joca.2005.10.010) Copyright © 2005 OsteoArthritis Research Society International Terms and Conditions

Fig. 2 The correlations of severity indices (●, ○) and mucopolysaccharide densities (▾, ▿) with serial time periods in each treated (Is, IIs, and IIIs; ●, ▾) and untreated control (Ic, IIc, and IIIc; ○, ▿) groups are shown in A–C. A: The relationships of the factors in Is and Ic; B: the relationships in IIs and IIc; C: the relationships in IIIs and IIIc. The original state (before induction of arthritis) with severity index 1.0 and mucopolysaccharide density 1.0, and the serial states were pre-, post-laser treatment and follow-up periods. The arrow (→) indicates the initial of laser treatment. Osteoarthritis and Cartilage 2006 14, 377-383DOI: (10.1016/j.joca.2005.10.010) Copyright © 2005 OsteoArthritis Research Society International Terms and Conditions

Fig. 3 The correlation of mucopolysaccharide densities post-laser treatment and the histopathological scores during the follow-up. Osteoarthritis and Cartilage 2006 14, 377-383DOI: (10.1016/j.joca.2005.10.010) Copyright © 2005 OsteoArthritis Research Society International Terms and Conditions