SYK activity is required for anti-IgM–induced DNA synthesis.

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Presentation transcript:

SYK activity is required for anti-IgM–induced DNA synthesis. SYK activity is required for anti-IgM–induced DNA synthesis. (A and B) An example of splenic B cells from wild-type (A) and Syk-AQL (B) mice treated with (α-IgM) or without (Control) anti‐IgM F(ab′)2 in the absence or presence of 3-MB-PP1 (3MB) (10 μM) for 48 h. Cells were examined by flow cytometry for the incorporation of EdU into DNA. (C) Data represent the mean ± SEM for separate analyses of DNA synthesis from four wild-type (closed bars) or Syk-AQL (open bars) mice. Means were compared by Student t test. *p < 0.0005. Wen-Horng Wang et al. ImmunoHorizons 2019;3:254-261 Copyright © 2019 The Authors