Xiang-Yu Chen, Dieter Enders Chem

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Multisubstituted Unnatural Prolines for Asymmetric Catalytic Domino Reactions Xiang-Yu Chen, Dieter Enders Chem Volume 4, Issue 1, Pages 21-23 (January 2018) DOI: 10.1016/j.chempr.2017.12.007 Copyright © 2017 Elsevier Inc. Terms and Conditions

Scheme 1 The Novel Asymmetric Organocatalytic Domino Reaction Employing a Catalytic System Based on Multisubstituted Unnatural Prolines (A) The multisubstituted-unnatural-proline derivative 1 catalyzed the domino reactions of ketones, nitroalkenes, and carboxylic acids. (B) Application of the new domino strategy for the asymmetric synthesis of (+)-pancracine. (C) Significant steps of the proposed reaction mechanism. Chem 2018 4, 21-23DOI: (10.1016/j.chempr.2017.12.007) Copyright © 2017 Elsevier Inc. Terms and Conditions