A) The neoplastic cells have medium-to-large size, abundant cytoplasm and enlarged, irregular nuclei. b) Immunohistochemical stain for CD79a is positive,

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a) The neoplastic cells have medium-to-large size, abundant cytoplasm and enlarged, irregular nuclei. b) Immunohistochemical stain for CD79a is positive, demonstrating the B-cell origin of the neoplastic cells. c) Proliferation marker Ki67 is positive in 80... a) The neoplastic cells have medium-to-large size, abundant cytoplasm and enlarged, irregular nuclei. b) Immunohistochemical stain for CD79a is positive, demonstrating the B-cell origin of the neoplastic cells. c) Proliferation marker Ki67 is positive in 80–90% of the neoplastic cells. d) Diffuse proliferation of large neoplastic lymphoid cells, infiltrating the lung parenchyma. Magnification: a) ×40; b–d) ×20. Evangelia Panagiotidou et al. Breathe 2018;14:e123-e127 ©2018 by European Respiratory Society