Kathryn J. Wiggins, Darren J. Kelly Kidney International

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Presentation transcript:

Aliskiren: a novel renoprotective agent or simply an alternative to ACE inhibitors? Kathryn J. Wiggins, Darren J. Kelly Kidney International Volume 76, Issue 1, Pages 23-31 (July 2009) DOI: 10.1038/ki.2009.105 Copyright © 2009 International Society of Nephrology Terms and Conditions

Figure 1 Schematic diagram showing the mechanisms of action of the renin–angiotensin system and sites of action of antagonizing drugs (red squares). AT, angiotensin; BK, bradykinin; NO, nitric oxide; TGF-β, transforming growth factor-β. Kidney International 2009 76, 23-31DOI: (10.1038/ki.2009.105) Copyright © 2009 International Society of Nephrology Terms and Conditions

Figure 2 Chemical structure of aliskiren. Kidney International 2009 76, 23-31DOI: (10.1038/ki.2009.105) Copyright © 2009 International Society of Nephrology Terms and Conditions