Estrogenic Steroids Overall Organization of the Topic

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Estrogenic Steroids Overall Organization of the Topic Structure and nomenclature of natural estrogens - Estradiol, estrone, and estriol Biosynthesis and metabolism of estradiol Synthetic estrogens - Schuler’s hypothesis Estrogen antagonists - clomiphene and tamoxifen 8/5/2019 MEDC 603 Steroids

Estrogenic Steroids Structure and Nomenclature of Natural Estrogens Estradioll Estrone Estriol intramuscular intramuscular oral 100% 33% 1.6% estr-1,3,5-triene- 3,17b-diol 3-hydroxy-estr-1,3,5 -triene-17-one estr-1,3,5-triene- 3,16a,17b-triol 8/5/2019 MEDC 603 Steroids

Biosynthesis and Metabolism of Estradiol cholesterol pregnenolone testosterone estriol estrone estradiol conjugation to glucuronides, sulfates, etc…. 8/5/2019 MEDC 603 Steroids

Synthetic Estrogenic ethinyl-estradiol diethylstilbestrol chlorotrianisene dienestrol 8/5/2019 MEDC 603 Steroids

Synthetic Estrogenic Schuler’s Hypothesis for Synthetic Estrogens 8/5/2019 MEDC 603 Steroids

Synthetic Estrogenic 8/5/2019 MEDC 603 Steroids

Estrogen Antagonists chlorotrianisene clomiphene (estrogenic) (anti-estrogenic) tamoxifen (anti-estrogenic) 8/5/2019 MEDC 603 Steroids

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