Development of atopic dermatitis according to age of onset and association with early- life exposures Caroline Roduit, MD, MPH, Remo Frei, PhD, Georg.

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Presentation transcript:

Development of atopic dermatitis according to age of onset and association with early- life exposures Caroline Roduit, MD, MPH, Remo Frei, PhD, Georg Loss, PhD, Gisela Büchele, MPH, Juliane Weber, MD, Martin Depner, PhD, Susanne Loeliger, MLS, Marie-Laure Dalphin, MD, Marjut Roponen, PhD, Anne Hyvärinen, PhD, Josef Riedler, MD, Jean-Charles Dalphin, MD, PhD, Juha Pekkanen, MD, Erika von Mutius, MD, MSc, Charlotte Braun-Fahrländer, MD, Roger Lauener, MD Journal of Allergy and Clinical Immunology Volume 130, Issue 1, Pages 130-136.e5 (July 2012) DOI: 10.1016/j.jaci.2012.02.043 Copyright © 2012 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 1 Association between food item introduction in the first year of life and atopic dermatitis with onset after the first year of life stratified by parental allergies. *Adjusted for farmer, center, breast-feeding, and parental history of allergies (ever eczema, hay fever, or asthma). For dairy products: introduction in the first year of life compared with no introduction before 1 year of age. For vegetables or fruits: introduction in the first 6 months of life compared with no introduction before 6 months of age. Journal of Allergy and Clinical Immunology 2012 130, 130-136.e5DOI: (10.1016/j.jaci.2012.02.043) Copyright © 2012 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 2 Association between increasing numbers of different major food items (n = 6) introduced in the first year of life and atopic dermatitis (AD) with onset after the first year of life. *Diversity score with major food items: vegetables or fruits, any cereals, meat, bread, cake, and yogurt. Journal of Allergy and Clinical Immunology 2012 130, 130-136.e5DOI: (10.1016/j.jaci.2012.02.043) Copyright © 2012 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E1 Association between increasing numbers of all different food items (n = 15) introduced in the first year of life and atopic dermatitis (AD) with onset after the first year of life. *Food items (n = 15): any cow's milk, yogurt, other milk products, eggs, nuts, vegetables or fruits, cereals, bread, meat, fish, soy, margarine, butter, cake, and chocolate. Journal of Allergy and Clinical Immunology 2012 130, 130-136.e5DOI: (10.1016/j.jaci.2012.02.043) Copyright © 2012 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E2 Association between increasing numbers of all different food items excluding major foods (n = 9) introduced in the first year of life and atopic dermatitis (AD) with onset after the first year of life. *Food items (n = 9): any cow's milk, other milk products, eggs, nuts, fish, soy, margarine, butter, and chocolate. Journal of Allergy and Clinical Immunology 2012 130, 130-136.e5DOI: (10.1016/j.jaci.2012.02.043) Copyright © 2012 American Academy of Allergy, Asthma & Immunology Terms and Conditions