Effect of sevelamer versus calcium-based binders on all-cause mortality in patients with CKD. Compared with calcium-based binders (CBBs), sevelamer significantly.

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Effect of sevelamer versus calcium-based binders on all-cause mortality in patients with CKD. Compared with calcium-based binders (CBBs), sevelamer significantly lowered all-cause mortality in patients with CKD stages 3–5 and on dialysis. 95% CI, 95% confid... Effect of sevelamerversus calcium-based binders on all-cause mortality in patients with CKD. Compared with calcium-based binders (CBBs), sevelamer significantly lowered all-cause mortality in patients with CKD stages 3–5 and on dialysis. 95% CI, 95% confidence interval; BRiC, phosphate binder Impact on Bone Remodeling and Coronary Calcification; CARE, Calcium Acetate Renagel Evaluation; CARE-2, Calcium Acetate Renagel Evaluation-2; DCOR, Dialysis Clinical Outcomes Revisited; df, degree of freedom; INDEPENDENT-HD, Reduce Cardiovascular Calcifications to Reduce QT Interval in Dialysis; M-H, Mantel–Haenszel. Leena Patel et al. CJASN 2016;11:232-244 ©2016 by American Society of Nephrology