Fig. 3 Exercise training enhances neuronal activity in vivo.

Slides:

Advertisements

Similar presentations

Fig. 4 The extracellular domain of sortilin is sufficient for BDNF/TrkB signaling. The extracellular domain of sortilin is sufficient for BDNF/TrkB signaling.

Advertisements

Fig. 4 3D reconfiguration of liquid metals for electronics.

Fig. 2 AdOPG transduction changes RANKL/OPG homeostasis in primary hMSCs differentiated on Col-GAG and MC-GAG. AdOPG transduction changes RANKL/OPG homeostasis.

Fig. 5 MicroLED array with 3D liquid metal interconnects.

Fig. 3 Sortilin deletion unmasks NTSR2 signaling.

Fig. 2 Reconfiguration of liquid metals into 3D structures.

Fig. 1 High-resolution printing of liquid metals.

Fig. 3 The electrical contact of direct-printed and reconfigured liquid metals. The electrical contact of direct-printed and reconfigured liquid metals.

Fig. 2 Global production, use, and fate of polymer resins, synthetic fibers, and additives (1950 to 2015; in million metric tons). Global production, use,

Fig. 4 INS spectra of different human bones from the Roman period [humerus, ulna, femur, and fibula from the same skeleton, Guidonia-Montecelio, Italy.

Fig. 2 CFD results. CFD results. Results of CFD simulations in horizontal (left column) and vertical (right column) cross-sections. All models oriented.

Vibrational spectra of medieval human bones (Leopoli-Cencelle, Italy)

Fig. 1 Characterization of Suv420h dKO mice.

Fig. 1 Map of water stress and shale plays.

Fig. 3 Tracing Poynting flux along Polar’s orbit during a period of 28 days, which includes a moderate storm and a major storm. Tracing Poynting flux along.

Fig. 2 Exercise training potentiates synaptic transmissions via mTOR activation. Exercise training potentiates synaptic transmissions via mTOR activation.

Fig. 1 Examples of experimental stimuli and behavioral performance.

Fig. 4 Resynthesized complex boronic acid derivatives based on different scaffolds on a millimole scale and corresponding yields. Resynthesized complex.

Fig. 4 The activation of mTOR is necessary for exercise-enhanced axonal myelination in the CC region. The activation of mTOR is necessary for exercise-enhanced.

Fig. 6 Comparison of properties of water models.

Fig. 1 Mean and median RCR (Relative Citation Ratio) of Roadmap Epigenomics Program research articles for each year. Mean and median RCR (Relative Citation.

Fig. 2 Influence of the Roadmap Epigenomics Program on the field of epigenomics research. Influence of the Roadmap Epigenomics Program on the field of.

Fig. 2 HHKO mice exhibit improved glucose tolerance by increasing plasma incretin levels and insulin secretion. HHKO mice exhibit improved glucose tolerance.

Fig. 3 Scan rate effects on the layer edge current.

Fig. 1 TED design and fabrication process.

Fig. 3 Implantation of the battery-free optofluidic nerve cuff system and its impact on animal behavior and nerve health. Implantation of the battery-free.

Fig. 3 Rotation experiment, setup.

Full-frame single image recording the violation of a Bell inequality

Fig. 1 Product lifetime distributions for the eight industrial use sectors plotted as log-normal probability distribution functions (PDF). Product lifetime.

FTIR-ATR spectra of Neolithic faunal bones (Mora Cavorso cave, Italy)

Fig. 1 Concept of the livestock transition in China between 1980 and Concept of the livestock transition in China between 1980 and The left-

Fig. 1 Schematic illustration of the preparation and potential application of FMSMs. Schematic illustration of the preparation and potential application.

Fig. 3 FcRL1 is passively recruited into B cell immunological synapses upon BCR engagement in primary spleen B cells. FcRL1 is passively recruited into.

Fig. 1 Parameterization and temporal distribution of carbon isotopic events in the database. Parameterization and temporal distribution of carbon isotopic.

Fig. 1 Distribution of total and fake news shares.

Fig. 2 2D QWs of different propagation lengths.

Fig. 1 Structure of L10-IrMn.

Fig. 1 Schematic illustration and atomic-scale rendering of a silica AFM tip sliding up and down a single-layer graphene step edge on an atomically flat.

Fig. 3 Load dependence of friction force and corresponding COF.

Fig. 1 Histograms of the number of first messages received by men and women in each of our four cities. Histograms of the number of first messages received.

Fig. 5 Schematic phase diagrams of Ising spin systems and Mott transition systems. Schematic phase diagrams of Ising spin systems and Mott transition systems.

Characteristics of ultrathin single-crystalline semiconductor films

Fig. 4 Praying Prophet by Lorenzo Monaco: Mapping lake pigments and associated substrate. Praying Prophet by Lorenzo Monaco: Mapping lake pigments and.

Fig. 1 Cross-sectional images of He-implanted V/Cu/V samples.

Fig. 2 Magnetic properties of FGT/Pt bilayer.

Contrast agent uptake for the four different groups of MMA mice

Fig. 3 Production of protein and Fe(II) at the end of growth correlated with increasing concentrations of ferrihydrite in the media that contained 0.2.

Fig. 2 Schematic drawings of Göbekli Tepe skulls.

Fig. 4 Dox-CBD-SA treatment shows reduced toxicity.

Fig. 2 Top 10 countries, ecoregions, conservation hotspots, and KBAs with the largest area of restoration hotspots. Top 10 countries, ecoregions, conservation.

Fig. 5 Comparison of the liquid products generated from photocatalytic CO2 reduction reactions (CO2RR) and CO reduction reactions (CORR) on two catalysts.

Fig. 1 Experimental strategy and elemental and morphological analysis of 3D/2D perovskite bilayer. Experimental strategy and elemental and morphological.

Fig. 1 Location of the Jirzankal Cemetery.

Fig. 4 CO2 emission changes triggered by the JJJ clean air policy.

Fig. 6 Stabilization of hippocampal signaling over sleep.

Fig. 3 Comparisons of NDVI trends over the globally vegetated areas from 1982 to Comparisons of NDVI trends over the globally vegetated areas from.

Fig. 6 IVIS Lumina scan of mice and of their organs after intravenous administration of fluorescent LENK-SQ-Am NPs or control fluorescent dye solution.

Fig. 1 Schematic depiction of a paradigm for rapid and guided discovery of materials through iterative combination of ML with HiTp experimentation. Schematic.

Fig. 4 Spatial mapping of the distribution and intensity of industrial fishing catch. Spatial mapping of the distribution and intensity of industrial fishing.

Fig. 4 Single-particle contact angle measurements.

ATP analogs have little effect on the conformation of the 2CARD domain

Fig. 2 Supraballs and films from binary SPs.

Fig. 3 Performance of the generative model G, with and without stack-augmented memory. Performance of the generative model G, with and without stack-augmented.

Fig. 4 Behavior of resistance peak near density nm = 5.

Fig. 2 Comparison between the different reflective metasurface proposals when θi = 0° and θr = 70°. Comparison between the different reflective metasurface.

Comparison of STM data on point impurities with DFT calculations

Fig. 1 Architected materials fabrication by projection microstereolithography–based additive manufacturing using poly(ethylene glycol) diacrylate resin.

Fig. 5 Phototransduction mechanisms.

Fig. 3 Evaluation of PTMAO immunogenicity.

Fig. 5 CD19-tPSMA(N9del) CAR T cell numbers in mouse and human.

Presentation transcript:

Fig. 3 Exercise training enhances neuronal activity in vivo. Exercise training enhances neuronal activity in vivo. (A) Illustrations of in vivo calcium recordings for apical dendrites and somas of L5PRN. (B) Schematic diagram of experimental protocols. Mice received AAV-GCaMP6s virus injection before 21-day treadmill training. Rapamycin was administrated every 3 days. At the end of exercise training, calcium imaging was performed. (C) Coronal section of mouse primary motor cortex showing GCaMP6s-transfected neurons after 3 weeks. (D) Representative z-stacked imaging planes (left) and calcium fluorescent traces (right) obtained from apical dendrites (top) and somas (bottom) of L5PRN. White arrowheads, active apical dendrite or somas. (E) Quantification of calcium peak ΔF/F0 values in apical dendrites (top) and somas (bottom). Runner mice showed significantly higher peak values (apical dendrite: one-way ANOVA, F3,195 = 16.89, P < 0.0001; Tukey post hoc comparison, q195 = 10.58, P < 0.0001 for nonrunner + saline versus runner + saline and q27 = 12.33, P < 0.0001 for runner + saline versus runner + rapamycin; soma: F3,456 = 14.78, P < 0.0001; q456 = 8.683 and P < 0.0001 for nonrunner + saline versus runner + saline and q456 = 12.03, P < 0.0001 for runner + saline versus runner + rapamycin). ***P < 0.001. n = 6 animals in each group. Error bars, SEM. Kai Chen et al. Sci Adv 2019;5:eaaw1888 Copyright © 2019 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).