Fig. 3 H3.1-dependent propagation of H3K27me3 maintains the memory of silencing during DNA replication. H3.1-dependent propagation of H3K27me3 maintains.

Slides:

Advertisements

Similar presentations

Soft robotic device applied to the RV in a pressure overload model of RHF. Soft robotic device applied to the RV in a pressure overload model of RHF. (A.

Advertisements

Cytotoxicity of MSP samples to normal and cancer cell lines.

Nuclear calcium signaling drives nuclear actin polymerization in T cells. Nuclear calcium signaling drives nuclear actin polymerization in T cells. (A)

FIP200 maintains microRNA1198-5p expression via Ago2 in naïve T cells.

Antitumor effect of local cancer immunotherapy treatment toward distant B16F10 tumors. Antitumor effect of local cancer immunotherapy treatment toward.

Ex vivo testing of the soft robotic devices.

Human cells produce type I and III IFNs upon Af stimulation.

Tukey boxplots overlaid on data points from objective and subjective measures, displaying results from study 1. Tukey boxplots overlaid on data points.

Persistent TCR–pMHC-I signaling drives the formation and maintenance of exhausted-like TRM cells. Persistent TCR–pMHC-I signaling drives the formation.

Differentiation of AZD4785 from MAPK pathway inhibitors in vitro

TCR signaling is required for exhausted-like TRM cell formation and maintenance. TCR signaling is required for exhausted-like TRM cell formation and maintenance.

Fig. 2 The SOS response is required for persistence to ofloxacin but not prior treatment. The SOS response is required for persistence to ofloxacin but.

Immune cell recruitment after the NIR-boosted and MN-mediated cancer immunotherapy. Immune cell recruitment after the NIR-boosted and MN-mediated cancer.

Fig. 3 scRNA-seq detects early transcriptional events during specification of embryonic cell states. scRNA-seq detects early transcriptional events during.

FIP200 maintains microRNA1198-5p expression via Ago2 in naïve T cells.

Antitumor effect of local cancer immunotherapy treatment in various tumor models. Antitumor effect of local cancer immunotherapy treatment in various tumor.

Cell viability tests. Cell viability tests. SEM images of (A) MC3T3-E1 cells and (B) MSCs on days 1, 3, and 5 of culture. (C) Survival rates of MC3T3-E1.

Fig. 3 Conditionally expressed CAR using Notch as a signal induction and response pathway system. Conditionally expressed CAR using Notch as a signal induction.

Microrobots with different cell-carrying capacities under different grid lengths (lg) and burr lengths (lb). Microrobots with different cell-carrying capacities.

Fig. 4 p100/TSN enables E2F1 to interact with alternatively spliced transcripts. p100/TSN enables E2F1 to interact with alternatively spliced transcripts.

Biological consequence of SENP7 alternative splicing for E2F1 activity

Fig. 1 Examples of experimental stimuli and behavioral performance.

Fig. 5 E2F1 also interacts with alternatively spliced transcripts from the MECOM gene. E2F1 also interacts with alternatively spliced transcripts from.

Fig. 2 The glucose binding and charge-switch study.

Soft robotic device applied to the RV in a pressure overload model of RHF. Soft robotic device applied to the RV in a pressure overload model of RHF. (A.

Fig. 4 Device accuracy results (n = 32 users).

Fig. 1. Potent and selective down-regulation of KRAS mRNA and protein by AZD4785 in vitro and in vivo. Potent and selective down-regulation of KRAS mRNA.

Fig. 1. CAR4 and CAR8 cells demonstrate in vitro and in vivo antileukemic efficacy. CAR4 and CAR8 cells demonstrate in vitro and in vivo antileukemic efficacy.

Fig. 5 EGLN2-mediated HIF1A down-regulation promotes ferroptosis.

BMS blocks functional responses in primary immune cells driven by IFNα

Drug response profiles and experimental validation.

Fig. 1 Bioinspired design of AAD for promoting wound contraction.

The two modalities for the multitask condition.

Fig. 4 HRI regulates BCL11A levels.

Fig. 2 HRI depletion elevates γ-globin in HUDEP2 cells.

Fig. 5 Conceptual diagram of the impact of acid deposition on calcium cycling and subsequent plant water use. Conceptual diagram of the impact of acid.

Fig. 6 RUNX/CBFB interaction inhibitor, Ro5-3335, significantly decreases mouse neurofibroma growth in vivo. RUNX/CBFB interaction inhibitor, Ro5-3335,

Fig. 2 Expressions of cll, abd-A, and Abd-B by qRT-PCR.

Fig. 2 2D QWs of different propagation lengths.

Fig. 7 LPS enhances cochlear TRPV1 expression and GTTR uptake in vivo.

In situ concurrent removal of MRSA bacteria and MRSA-secreting PFTs by RBC-PL-robots. In situ concurrent removal of MRSA bacteria and MRSA-secreting PFTs.

Galloping-like gait with the design of a two-legged robot.

AEGIS autonomous targeting process.

Fig. 2 Nucleation is maintained but spreading is inhibited by roscovitine treatment. Nucleation is maintained but spreading is inhibited by roscovitine.

Fig. 3 Local Maraba treatment of TNBC tumors provides long-term systemic protection. Local Maraba treatment of TNBC tumors provides long-term systemic.

Deformability and stability of RBC microswimmers squeezing through confined spaces smaller than their size. Deformability and stability of RBC microswimmers.

Fig. 4. Paclitaxel promotes the expression of invasive isoforms of MENA in the primary breast cancer microenvironment. Paclitaxel promotes the expression.

Fig. 3 Collective modes of charge order in LBCO propagate diffusively.

Storm protection services

Fig. 1 Time course of growth parameters for acetate-grown cultures of M. acetivorans with and without supplements. Time course of growth parameters for.

Fig. 3 Production of protein and Fe(II) at the end of growth correlated with increasing concentrations of ferrihydrite in the media that contained 0.2.

Requirement of ARFs for ATXR2 function.

Fig. 4 Differential histone modifications at promoters in various brain cell populations. Differential histone modifications at promoters in various brain.

Fig. 4 Functional confirmation of genes associated with isopropanol tolerance in E. faecium. Functional confirmation of genes associated with isopropanol.

Fig. 4 Adenosine A2BR signaling promote osteogenic and inhibit osteoclast differentiation in vitro. Adenosine A2BR signaling promote osteogenic and inhibit.

Combination therapies targeting CDs with KRASG12C differ in their ability to promote S-IIP target engagement. Combination therapies targeting CDs with.

Fig. 1 Distribution of forest tree mycorrhizal types and their associated factors in forests of the contiguous United States. Distribution of forest tree.

Fig. 6 Experimental setup and properties of the IP screen.

Discrimination accuracy across conditions.

Fig. 4 The relationship between the total mean absolute momentum disturbance 〈∣p∣〉zB (in units of ℏ/D) and fringe visibility V. The relationship between.

Fig. 6 Stabilization of hippocampal signaling over sleep.

Fig. 3 Effects of ASO and eGLP1-ASO conjugates on gene expression and protein levels in vitro in cell lines and primary mouse islet cells. Effects of ASO.

Fig. 3 Comparisons of NDVI trends over the globally vegetated areas from 1982 to Comparisons of NDVI trends over the globally vegetated areas from.

Fig. 3 Heterologous TRPV1-mediated uptake of gentamicin is attenuated by extracellular [Ca2+]. Heterologous TRPV1-mediated uptake of gentamicin is attenuated.

Fig. 1 B2 RNA directly inhibits transcription.

REV-ERBα deficiency alters the epigenetic landscape and differentially affects clock gene expression in ILC3 subsets. REV-ERBα deficiency alters the epigenetic.

Fig. 3 Gene expression analysis in 48-plex drug treatment experiments.

Fig. 2 HAdV-D26K shares key binding residues with sialic acid–using adenoviruses and exploits sialic acid to infect cells. HAdV-D26K shares key binding.

Fig. 2. Cellular response to FolamiRs in vitro.

Cxxc1-deficient TH17 cells exhibit a Treg cell–like expression profile

Presentation transcript:

Fig. 3 H3.1-dependent propagation of H3K27me3 maintains the memory of silencing during DNA replication. H3.1-dependent propagation of H3K27me3 maintains the memory of silencing during DNA replication. (A) GR-LhG4 expressed under the control of the HTR13 promoter (solid arrow) can be activated by DEX and subsequently binds to the pOp3 promoter to activate amiRHTR13-1 transcription (dashed arrow). (B) Experimental design of treatment with DEX and the cell cycle inhibitors olomoucine (OLO) and roscovitine (ROS). (C) Gene expression upon DEX and cell cycle inhibitor treatment. (D) Relative H3K27me3 levels at AT5G60250 and AT5G60610 chromatin in seedlings treated with DEX and cell cycle inhibitors. For all experiments, error bars represent SD from three biological replicates. Unpaired t test: *P < 0.05; **P < 0.01; ***P < 0.001; n.s., not significant. Danhua Jiang, and Frédéric Berger Science 2017;357:1146-1149 Copyright © 2017 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works