Volume 125, Issue 2, Pages (August 2003)

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Volume 125, Issue 2, Pages 591-596 (August 2003) Pain as a complication of use of opiate antagonists for symptom control in cholestasis Christine A Mcrae, Martin I Prince, Mark Hudson, Christopher P Day, Oliver F.W James, David E.J Jones Gastroenterology Volume 125, Issue 2, Pages 591-596 (August 2003) DOI: 10.1016/S0016-5085(03)00879-5

Figure 1 Incidence and kinetics of initial discontinuation of opiate antagonist therapy because of unacceptable side effects in patients receiving initial significant symptomatic benefit. Time scale is after the introduction of opiate antagonist therapy. One patient subsequently restarted oral opiate antagonist therapy at a lower dose with partial pruritus control being achieved in the absence of side effects. Gastroenterology 2003 125, 591-596DOI: (10.1016/S0016-5085(03)00879-5)