Tissue oxygenation index is a useful monitor of histologic and neurologic outcome after cardiopulmonary bypass in piglets Ikuo Hagino, MD, Vesa Anttila,

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Presentation transcript:

Tissue oxygenation index is a useful monitor of histologic and neurologic outcome after cardiopulmonary bypass in piglets Ikuo Hagino, MD, Vesa Anttila, MD, David Zurakowski, PhD, Lennart F. Duebener, MD, Hart G.W. Lidov, MD, Richard A. Jonas, MD The Journal of Thoracic and Cardiovascular Surgery Volume 130, Issue 2, Pages 384-392 (August 2005) DOI: 10.1016/j.jtcvs.2005.02.058 Copyright © 2005 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 Experimental protocol depicting bypass conditions. All animals underwent the pH-stat strategy. NIRS signals were recorded every 10 seconds after induction of anesthesia and for 3 hours after weaning from CPB. Hct, Hematocrit. The Journal of Thoracic and Cardiovascular Surgery 2005 130, 384-392DOI: (10.1016/j.jtcvs.2005.02.058) Copyright © 2005 The American Association for Thoracic Surgery Terms and Conditions

Figure 2 Changes in Hbo2 determined by means of NIRS. LFB, Low-flow bypass. The Journal of Thoracic and Cardiovascular Surgery 2005 130, 384-392DOI: (10.1016/j.jtcvs.2005.02.058) Copyright © 2005 The American Association for Thoracic Surgery Terms and Conditions

Figure 3 Changes in TOI at 3 different low-flow rates (10, 25, 50 mL·kg−1·min−1). LFB, Low-flow bypass. The Journal of Thoracic and Cardiovascular Surgery 2005 130, 384-392DOI: (10.1016/j.jtcvs.2005.02.058) Copyright © 2005 The American Association for Thoracic Surgery Terms and Conditions

Figure 4 A significant inverse correlation was identified between average TOI and NDS on the first postoperative day (Pearson r = −0.50, P = .002). The Journal of Thoracic and Cardiovascular Surgery 2005 130, 384-392DOI: (10.1016/j.jtcvs.2005.02.058) Copyright © 2005 The American Association for Thoracic Surgery Terms and Conditions

Figure 5 Significant difference in mean NDS according to TOI level. POD-1, Postoperative day 1. The Journal of Thoracic and Cardiovascular Surgery 2005 130, 384-392DOI: (10.1016/j.jtcvs.2005.02.058) Copyright © 2005 The American Association for Thoracic Surgery Terms and Conditions