One-year increase of Coll 2-1, a new marker of type II collagen degradation, in urine is highly predictive of radiological OA progression M.A. Deberg, Ph.D., A.H. Labasse, B.Sc., J. Collette, Ph.D., L. Seidel, B.Sc., J.-Y. Reginster, M.D., Ph.D., Y.E. Henrotin, Ph.D. Osteoarthritis and Cartilage Volume 13, Issue 12, Pages 1059-1065 (December 2005) DOI: 10.1016/j.joca.2005.06.014 Copyright © 2005 OsteoArthritis Research Society International Terms and Conditions
Fig. 1 Progression of joint damage over 3 years according to quartile of 1-year variation of Coll 2-1 (▪) and Coll 2-1 NO2 (□). Bars represent the mean value (SD) of the JSW in the highest (Q4: 1-year variation of Coll 2-1: >+1.05nM/mM and Coll 2-1 NO2: ≥±0.007nM/mM) and lowest quartiles (Q1: 1-year variation of Coll 2-1: <−3.11nM/mM and Coll 2-1 NO2: ≤−0.010nM/mM). Osteoarthritis and Cartilage 2005 13, 1059-1065DOI: (10.1016/j.joca.2005.06.014) Copyright © 2005 OsteoArthritis Research Society International Terms and Conditions