Volume 56, Pages S171-S173 (July 1999)

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Volume 56, Pages S171-S173 (July 1999) Phospholipase A2 activity in ox-LDL-stimulated mesangial cells and modulation by α- tocopherol Mituru Ozaki, Yoichi Yamada, M.D, Katsumi Matoba, Haruhisa Otani, Masatoshi Mune, Susumu Yukawa, Wataru Sakamoto Kidney International Volume 56, Pages S171-S173 (July 1999) DOI: 10.1046/j.1523-1755.1999.07144.x Copyright © 1999 International Society of Nephrology Terms and Conditions

Figure 1 Phospholipase A2 (PLA2) activity of rat mesangial cells exposed to native low density lipoprotein (LDL) or oxidized LDL. Data express the percentage of the control and mean ±SE. Symbols are: (□) native LDL; (▪) oxidized LDL. Kidney International 1999 56, S171-S173DOI: (10.1046/j.1523-1755.1999.07144.x) Copyright © 1999 International Society of Nephrology Terms and Conditions

Figure 2 Effects of α-tocopherol (α-Toc) on oxidized low density lipoprotein (LDL)-induced phospholipase A2 (PLA2) activity in rat mesangial cells. After 24 hours of preincubation in medium containing 50 μMα-Toc or probucol (0.25% ethanol), rat mesangial cells (1 to 3 × 106 cells) were incubated for 24 hours in medium containing 200 μg/ml of oxidized LDL. Data express mean ± SE. Kidney International 1999 56, S171-S173DOI: (10.1046/j.1523-1755.1999.07144.x) Copyright © 1999 International Society of Nephrology Terms and Conditions