Global analysis of human, marmoset and mouse preimplantation stages.

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Global analysis of human, marmoset and mouse preimplantation stages. Global analysis of human, marmoset and mouse preimplantation stages. (A) Summary of single-cell RNA-seq data considered in this study. Individual transcriptome numbers are indicated for each developmental stage. MYA, million years. (B) Phase-contrast images of marmoset embryos processed for transcriptional profiling. (C-E) PCA of single cell embryo data for each species (FPKM>0). (F) Pearson correlation distance of preimplantation stages of human (red), marmoset (orange) and mouse (blue), with stages indicated below as in C. (G-I) Mutual information entropy between preimplantation stages. Thorsten Boroviak et al. Development 2018;145:dev167833 © 2018. Published by The Company of Biologists Ltd