Incidence of gallstone disease in women (top) and men (bottom) per 100 000 person-years. Incidence of gallstone disease in women (top) and men (bottom) per 100 000 person-years. Note that the difference between the curves is an estimate of crude incidence rates. Kari Hemminki et al. BMJ Open Gastroenterol 2017;4:e000188 © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.