Antral follicle counts are strongly associated with live-birth rates after assisted reproduction, with superior treatment outcome in women with polycystic.

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Presentation transcript:

Antral follicle counts are strongly associated with live-birth rates after assisted reproduction, with superior treatment outcome in women with polycystic ovaries Jan Holte, M.D., Ph.D., Thomas Brodin, M.D., Lars Berglund, M.Sc., Ph.D., Nermin Hadziosmanovic, M.Sc., Matts Olovsson, M.D., Ph.D., Torbjörn Bergh, M.D., Ph.D. Fertility and Sterility Volume 96, Issue 3, Pages 594-599 (September 2011) DOI: 10.1016/j.fertnstert.2011.06.071 Copyright © 2011 American Society for Reproductive Medicine Terms and Conditions

Figure 1 Pregnancy rate (%) per started stimulation (solid line) relative to log transformed antral follicle count (AFC), with confidence interval (dotted lines). Pregnancy rates increased (log−) linearly and leveled out above the AFC ∼30. The corresponding graph for the live-birth rate described the same pattern. AF = antral follicles. Density (red) denotes the distribution after log transformation. The AFC numbers given along the x-axis are back-transformed for ease of interpretation. N = 4,308 IVF-ICSI treatment cycles. Fertility and Sterility 2011 96, 594-599DOI: (10.1016/j.fertnstert.2011.06.071) Copyright © 2011 American Society for Reproductive Medicine Terms and Conditions

Figure 2 Live-birth rates/oocyte pickup (%) relative to different ages at oocyte pickup (<34; 34–38; >38 years) within each antral follicle count-stratum (<5, 6–11, 12–23, and >23 antral follicles). Mean values ± standard error of the mean. N = 4,004 IVF-ICSI treatment cycles. AFC = antral follicle count. Fertility and Sterility 2011 96, 594-599DOI: (10.1016/j.fertnstert.2011.06.071) Copyright © 2011 American Society for Reproductive Medicine Terms and Conditions