Genes that escape MSCI are located peripheral to the repressive XY body. Genes that escape MSCI are located peripheral to the repressive XY body. Snapshots.

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Genes that escape MSCI are located peripheral to the repressive XY body. Genes that escape MSCI are located peripheral to the repressive XY body. Snapshots from 3D image files (Movies 2-13) of pachytene spermatocytes created from optical sections using Imaris software. DNA-FISH signals (blue) represent each specific gene locus. γ-H2AX (red) delineates the repressive XY body heterochromatin domain. Listed in each panel are the percentages of 30 cells examined for each gene in which the corresponding locus was found to be located outside of the XY body. Enrique Sosa et al. Development 2015;142:3791-3800 © 2015. Published by The Company of Biologists Ltd