Luigi Fontana, Linda Partridge Cell

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Promoting Health and Longevity through Diet: From Model Organisms to Humans Luigi Fontana, Linda Partridge Cell Volume 161, Issue 1, Pages 106-118 (March 2015) DOI: 10.1016/j.cell.2015.02.020 Copyright © 2015 Elsevier Inc. Terms and Conditions

Figure 1 Dietary Restriction Increases Healthy Lifespan in Diverse Single-Celled, Invertebrate, and Vertebrate Animals Cell 2015 161, 106-118DOI: (10.1016/j.cell.2015.02.020) Copyright © 2015 Elsevier Inc. Terms and Conditions

Figure 2 Dietary Restriction Modulates Multiple Systemic, Neural, and Cellular Mechanisms that Improve Health and Combat the Diseases of Aging Cell 2015 161, 106-118DOI: (10.1016/j.cell.2015.02.020) Copyright © 2015 Elsevier Inc. Terms and Conditions

Figure 3 The Effectors of Dietary Restriction, Including Timing of Food Intake, Specific Nutrients—Especially Proteins and Particular Amino Acids—the Gut Microbiome, and Longer-Term Mechanisms, Including Developmental Programming and Trans-generational Effects, Modulate Key Mechanisms Associated with Healthy Aging Cell 2015 161, 106-118DOI: (10.1016/j.cell.2015.02.020) Copyright © 2015 Elsevier Inc. Terms and Conditions