Hybrid Debranching With Endovascular Repair for Thoracoabdominal Aneurysms: A Comparison With Open Repair  Himanshu J. Patel, MD, Gilbert R. Upchurch,

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Hybrid Debranching With Endovascular Repair for Thoracoabdominal Aneurysms: A Comparison With Open Repair  Himanshu J. Patel, MD, Gilbert R. Upchurch, MD, Jonathan L. Eliason, MD, Enrique Criado, MD, John Rectenwald, MD, David M. Williams, MD, G. Michael Deeb, MD  The Annals of Thoracic Surgery  Volume 89, Issue 5, Pages 1475-1481 (May 2010) DOI: 10.1016/j.athoracsur.2010.01.062 Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Kaplan-Meier survival analysis comparing conventional open thoracoabdominal aneurysm repair (TAAA) to hybrid debranching repair. This actuarial analysis demonstrates that after either open or hybrid debranching thoracoabdominal aortic repair, there is no significant difference in Kaplan-Meier survival (mean survival open repair, 75 months versus hybrid debranching and thoracic endovascular repair, 81.1 months; p = 0.88). The Annals of Thoracic Surgery 2010 89, 1475-1481DOI: (10.1016/j.athoracsur.2010.01.062) Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 (A) Impact of diabetes on late survival. Diabetes was identified as an important independent predictor of late mortality (p = 0.052, odds ratio 4.5). This actuarial analysis demonstrates the significant time-dependent effects of diabetes on late survival, with 3-year survival in diabetic patients at 40% versus 80% for nondiabetics. (B) Impact of postoperative need for dialysis on late survival. The postoperative need for dialysis was an independent risk factor for late mortality on multivariate analysis (p < 0.001, odds ratio 8.6). This Kaplan-Meier analysis identifies decreased late survival in patients who underwent thoracoabdominal aortic aneurysm repair and had a postoperative dialysis (p < 0.001). The 3-year survival is 87.1% for those without a postoperative need for dialysis versus 32.8% for those requiring postoperative dialysis (p < 0.001). The Annals of Thoracic Surgery 2010 89, 1475-1481DOI: (10.1016/j.athoracsur.2010.01.062) Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Freedom from need for aortic reintervention or aortic rupture. By Kaplan-Meier analysis, the mean freedom from treatment failure (defined as need for reintervention or rupture) for the entire cohort was 91.6 ± 5.9 months (data not shown). When the analysis was stratified by type of repair there was no difference between groups. The 4-year freedom from treatment failure was 90.5 ± 4.7% for the open thoracoabdominal aortic aneurysm repair group versus 92.0 ± 5.4% for the hybrid debranching group (p = 0.41). The Annals of Thoracic Surgery 2010 89, 1475-1481DOI: (10.1016/j.athoracsur.2010.01.062) Copyright © 2010 The Society of Thoracic Surgeons Terms and Conditions