Figure 1 Correlation between en face Oil-Red O staining and aortic root lesion size vs. plasma cholesterol and ... Figure 1 Correlation between en face.

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J Exp Bot. 2017;68(17): doi: /jxb/erx352

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Figure 1 Correlation between en face Oil-Red O staining and aortic root lesion size vs. plasma cholesterol and ... Figure 1 Correlation between en face Oil-Red O staining and aortic root lesion size vs. plasma cholesterol and triglyceride. (A) Correlation of en face Oil-Red O staining vs. lesion size. Symbols used denote different murine atherosclerosis models (refer to key in F). (B) Correlation of lesion size vs. total plasma cholesterol. Dotted lines describe classification of total plasma cholesterol as per, normal levels (<100 mg/dL),<sup>1</sup><sup>,</sup><sup>3</sup> hypercholesterolaemia (>300 mg/dL, red)<sup>1</sup>, expected levels in ApoE<sup>−</sup><sup>/</sup><sup>−</sup> and Ldlr<sup>−</sup><sup>/</sup><sup>−</sup> mice fed western diet (1300–2000 mg/dL, purple and 1500–2000 mg/dL, green), respectively.<sup>1</sup><sup>,</sup><sup>2</sup> (C) Correlation of en face Oil-Red O staining vs. total plasma cholesterol. Dotted lines refer to plasma cholesterol levels as in (B). (D) Correlation of en face Oil-Red O staining vs. plasma triglyceride. (E) Correlation of lesion size vs. plasma triglyceride. Linear regression and Pearson correlation coefficients were calculated (95% CI, dotted lines). R<sup>2</sup> is reported along with level of significance. Data points represent the mean given in each publication. (F) Key for symbols of the different experimental models analysed. Unless provided in the caption above, the following copyright applies to the content of this slide: © The Author(s) 2018. Published by Oxford University Press on behalf of the European Society of Cardiology. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Cardiovasc Res, Volume 114, Issue 14, 05 June 2018, Pages 1845–1847, https://doi.org/10.1093/cvr/cvy140 The content of this slide may be subject to copyright: please see the slide notes for details.