A: Schematic representation of the heterogeneity of the lungs of patients with ARDS. Normal alveoli are subject to injury due to overdistention, whereas.

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A: Schematic representation of the heterogeneity of the lungs of patients with ARDS. Normal alveoli are subject to injury due to overdistention, whereas collapsed alveoli are subject to injury due to cyclic opening and closing throughout the respiratory cycle. A: Schematic representation of the heterogeneity of the lungs of patients with ARDS. Normal alveoli are subject to injury due to overdistention, whereas collapsed alveoli are subject to injury due to cyclic opening and closing throughout the respiratory cycle. B: Chest CT of a patient with ARDS. Note that the collapse and consolidation are primarily in the dependent lung zones. The nondependent regions appear relatively normal. Dean R Hess Respir Care 2015;60:1688-1704 (c) 2012 by Daedalus Enterprises, Inc.