Volume 54, Pages S195-S198 (September 1998)

Slides:

Advertisements

Similar presentations

Pathophysiology of renal fluid retention

Advertisements

Volume 63, Issue 2, Pages (February 2003)

Low protein diet mediated renoprotection in remnant kidneys: Renal autoregulatory versus hypertrophic mechanisms Karen A. Griffin, Maria Picken, Anita.

Renal manifestations in Fabry disease and therapeutic options

Volume 70, Issue 3, Pages (August 2006)

Differential connexin expression in preglomerular and postglomerular vasculature: Accentuation during diabetes Jianhong Zhang, Caryl E. Hill, Professor

Anemia management in chronic kidney disease

Volume 71, Issue 11, Pages (June 2007)

Karin Skov, Jens R. Nyengaard, Ardan Patwardan, Michael J. Mulvany

Regional citrate versus systemic heparin anticoagulation for continuous renal replacement in critically ill patients Demetrios J. Kutsogiannis, R.T.Noel.

Differential connexin expression in preglomerular and postglomerular vasculature: Accentuation during diabetes Jianhong Zhang, Caryl E. Hill, Professor

Volume 56, Pages S31-S36 (July 1999)

The Case ∣ Generalized petechiae and acute renal failure

Progression of renal failure and hypertensive nephrosclerosis

Karen A. Griffin, Maria M. Picken, George L. Bakris, Anil K. Bidani

Pathophysiology of renal fluid retention

Overcoming barriers that inhibit proper treatment of anemia

Christopher S. Wilcox, William J. Welch Kidney International

Intestinal phosphate absorption in a model of chronic renal failure

Effects of antihypertensive therapy on intrarenal angiotensin and bradykinin levels in experimental renal insufficiency Fiona E. Mackie, Timothy W. Meyer,

Volume 66, Pages S13-S17 (September 2004)

Comorbidity and confounding in end-stage renal disease

Volume 68, Issue 2, Pages (August 2005)

D. Batlle, P. Ramadugu, M.J. Soler Kidney International

A new era in phosphate binder therapy: What are the options?

Volume 70, Issue 11, Pages (December 2006)

Insulin resistance in African Americans

Volume 84, Issue 3, Pages (September 2013)

The epidemiology of chronic kidney disease

Volume 87, Issue 2, Pages (February 2015)

Saulo Klahr, Jeremiah J. Morrissey Kidney International

Volume 63, Issue 2, Pages (February 2003)

James D. House, Margaret E. Brosnan, John T. Brosnan

Public health in Africa: What is new—The context, the gains, the losses, the renewed public health, and the way forward D.A.N.C.O. Kaseje, Pamela Juma,

Volume 66, Issue 5, Pages (November 2004)

Elke Wühl, Otto Mehls, Franz Schaefer Kidney International

Recombinant human insulin-like growth factor-1 induces an anabolic response in malnourished CAPD patients Denis Fouque, Susy C. Peng, Eshan Shamir, Joel.

Structure, not just function

Volume 69, Issue 12, Pages (June 2006)

Volume 69, Issue 3, Pages (February 2006)

Efferent arteriole tubuloglomerular feedback in the renal nephron

The kidney, a cardiovascular risk marker, and a new target for therapy

Ruisheng Liu, Yilin Ren, Jeffrey L. Garvin, Oscar A. Carretero

Characteristics of isolated perfused juxtaglomerular apparatus

Lynda Anne Szczech, Ira L. Lazar Kidney International

Volume 68, Issue 4, Pages (October 2005)

Neurogenic factors and hypertension in renal disease

Recapitulation of phylogeny by ontogeny in nephrology

Harold M. Aukema, Ihsan Housini Kidney International

A man with a hole in his penis

It's not over till the last glomerulus forms

Volume 71, Issue 11, Pages (June 2007)

Opportunities for a chronic disease outreach program in China

Volume 79, Issue 5, Pages (March 2011)

Wei-Teing Chen, Horng-Chin Yan, Fu-Chiu Yu Kidney International

Clinical benefits of slowing the progression of renal failure

David Z. Levine, M.D., Michelle Iacovitti, Kevin D. Burns, Amy Slater

Volume 55, Pages S3-S16 (June 1999)

Hemodialysis and L-arginine, but not D-arginine, correct renal failure-associated endothelial dysfunction Malcolm F. Hand, William G. Haynes, David J.

Prostaglandins in macula densa function

Yilin Ren, M.D., Shuji Arima, Oscar A. Carretero, Sadayoshi Ito

Volume 54, Pages S207-S210 (September 1998)

The changing face of childhood nephrotic syndrome

Volume 53, Issue 4, Pages (April 1998)

Volume 66, Issue 2, Pages (August 2004)

Volume 75, Issue 5, Pages (March 2009)

D.J. Askenazi, D.I. Feig, N.M. Graham, S. Hui-Stickle, S.L. Goldstein

Volume 86, Issue 3, Pages (September 2014)

Morphology of the heart and arteries in renal failure

Epidemiologic data of renal diseases from a single unit in China: Analysis based on 13,519 renal biopsies Lei-Shi Li, Zhi-Hong Liu Kidney International

Presentation transcript:

Volume 54, Pages S195-S198 (September 1998) Insulin-like growth factor-I restores microvascular autoregulation in experimental chronic renal failure Jen-Jar Lin, Burkhard Tönshoff, Nathalie Bouriquet, Daniel Casellas, Frederick J. Kaskel, Leon C. Moore Kidney International Volume 54, Pages S195-S198 (September 1998) DOI: 10.1046/j.1523-1755.1998.06745.x Copyright © 1998 International Society of Nephrology Terms and Conditions

Figure 1 A perfused juxtamedullary nephron in a remnant kidney reduced by surgical excision. Visible are an afferent arteriole (A), efferent arteriole (E), glomerulus (G), and macula densa (M). The image is a composite of overlapping video fields. The bar in the upper left is 25 μm. Kidney International 1998 54, S195-S198DOI: (10.1046/j.1523-1755.1998.06745.x) Copyright © 1998 International Society of Nephrology Terms and Conditions

Figure 2 Autoregulation responses in mid-afferent arterioles (AA) segments from rats subjected to five-sixths nephrectomy by surgical excision (N = 7), cortical infarction (N = 5), or control sham surgery (N = 6). Shown are baseline responses (•) and responses during treatment with 10nm insulin-like growth factor-I (IGF-I; ○) or 10mm MnCl2 to block calcium channels (▪). Autoregulation in both chronic renal failure (CRF) groups was significantly impaired versus the sham controls [P < 0.05, two-way analysis of variance (ANOVA)] and was significantly enhanced by IGF-I in both CRF groups (P < 0.05, two-way repeated measures ANOVA). Kidney International 1998 54, S195-S198DOI: (10.1046/j.1523-1755.1998.06745.x) Copyright © 1998 International Society of Nephrology Terms and Conditions

Figure 3 Responses to topical application of 10 μm acetylcholine in mid-afferent arterioles (AA) segments from rats with five-sixths nephrectomy via surgical excision or cortical infarction and in sham controls. The responses in the infarction group were significantly smaller than in the other two groups (P < 0.05, analysis of variance and Student-Newman-Keuls test). Kidney International 1998 54, S195-S198DOI: (10.1046/j.1523-1755.1998.06745.x) Copyright © 1998 International Society of Nephrology Terms and Conditions