Effect of Nitric Oxide Gas on Platelets During Open Heart Operations

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Effect of Nitric Oxide Gas on Platelets During Open Heart Operations Karin Mellgren, Gösta Mellgren, Stefan Lundin, Åke Wennmalm, Hans Wadenvik The Annals of Thoracic Surgery Volume 65, Issue 5, Pages 1335-1341 (May 1998) DOI: 10.1016/S0003-4975(98)00160-X

Fig. 1 Platelet counts in the control and nitric oxide (NO) groups during cardiopulmonary bypass (CPB). The values are given as the mean plus or minus the standard error of the mean and were normalized to the values obtained before anesthesia. The difference between the two study groups was not statistically significant. The Annals of Thoracic Surgery 1998 65, 1335-1341DOI: (10.1016/S0003-4975(98)00160-X)

Fig. 2 Plasma β-thromboglobulin (BTG) levels in the control and nitric oxide (NO) groups during cardiopulmonary bypass (CPB). The values are given as the mean plus or minus the standard error of the mean. No statistically significant difference was observed between the two study groups. The Annals of Thoracic Surgery 1998 65, 1335-1341DOI: (10.1016/S0003-4975(98)00160-X)

Fig. 3 Platelet glycoprotein IB (GPIb) expression in the control and nitric oxide (NO) groups during cardiopulmonary bypass (CPB). The values are given as the mean plus or minus the standard error of the mean and were normalized to the values recorded before anesthesia. The difference between the two study groups was statistically significant (p = 0.035 by analysis of variance, treatment × time effect). The Annals of Thoracic Surgery 1998 65, 1335-1341DOI: (10.1016/S0003-4975(98)00160-X)

Fig. 4 Platelet membrane glycoprotein IIb/IIIa (GPIIb/IIIa) expression in the control and nitric oxide (NO) groups during cardiopulmonary bypass (CPB). The values are given as the mean plus or minus the standard error of the mean and were normalized to the values recorded before anesthesia. No statistically significant difference was observed between the two study groups. The Annals of Thoracic Surgery 1998 65, 1335-1341DOI: (10.1016/S0003-4975(98)00160-X)

Fig. 5 Plasma nitrate concentrations in the control and nitric oxide (NO) groups during cardiopulmonary bypass (CPB). The values are given as the mean plus or minus the standard error of the mean. No statistically significant difference was observed between the two study groups. The Annals of Thoracic Surgery 1998 65, 1335-1341DOI: (10.1016/S0003-4975(98)00160-X)

Fig. 6 Plasma hemoglobin concentrations in the control and nitric oxide (NO) groups during cardiopulmonary bypass (CPB). The values are given as the mean plus or minus the standard error of the mean. No statistically significant difference was observed between the two study groups. The Annals of Thoracic Surgery 1998 65, 1335-1341DOI: (10.1016/S0003-4975(98)00160-X)