Expression of transforming growth factor β1 in nerve fibers is related to dysmenorrhea and laparoscopic appearance of endometriotic implants  Stefano.

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Presentation transcript:

Expression of transforming growth factor β1 in nerve fibers is related to dysmenorrhea and laparoscopic appearance of endometriotic implants  Stefano Tamburro, M.D., Michel Canis, M.D., Eliane Albuisson, M.D., Ph.D., Pierre Dechelotte, M.D, Ph.D., Claude Darcha, M.D., Gérard Mage, M.D.  Fertility and Sterility  Volume 80, Issue 5, Pages 1131-1136 (November 2003) DOI: 10.1016/S0015-0282(03)01182-8

FIGURE 1 High index score of TGFβ1 was related to the highest dysmenorrhea index score (Spearman rho, P=.001). Tamburro. TGFβ1 nerve expression in endometriosis. Fertil Steril 2003. Fertility and Sterility 2003 80, 1131-1136DOI: (10.1016/S0015-0282(03)01182-8)

FIGURE 2 Marking of TGFβ1 in different endometriotic lesions (Kruskal-Wallis, P=.0001). Tamburro. TGFβ1 nerve expression in endometriosis. Fertil Steril 2003. Fertility and Sterility 2003 80, 1131-1136DOI: (10.1016/S0015-0282(03)01182-8)

FIGURE 3 (A), Nerve fiber in a red lesion shows high TGFβ1 expression. (B), Nerve fiber in a white lesion shows low TGFβ1 expression (transversal section). (C), Nerve fiber in a black lesion shows no TGFβ1 expression (transversal section). (D), Nerve fiber (arrow) in normal tissue shows no TGFβ1 expression (control group). Tamburro. TGFβ1 nerve expression in endometriosis. Fertil Steril 2003. Fertility and Sterility 2003 80, 1131-1136DOI: (10.1016/S0015-0282(03)01182-8)