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Copyright Notice This presentation is copyrighted by the Psychopharmacology Institute. Subscribers can download it and use it for professional use. The contents of the presentation may be modified, but the Psychopharmacology Institute logo must remain visible in all slides.

Psychopharmacology Algorithms: PTSD David N. Osser, MD, Associate Professor of Psychiatry Harvard Medical School Brockton Division of the VA Boston Healthcare System

The author has no financial relationships with any pharmaceutical or other commercial firms.

PTSD - Introduction PTSD Dysregulation of systems Neurotransmitters Neuroendocrine Neuroanatomical Susceptible to pharmacotherapy

PTSD - Introduction PTSD Dysregulation of systems Neurotransmitters Neuroendocrine Neuroanatomical Susceptible to pharmacotherapy Psychotherapy IS important: but not our focus here

About this algorithm Focus: evidence for efficacy Evidence-supported algorithm Reasoning behind each recommendation Focus: evidence for efficacy

About this algorithm Clinical experience is also important Evidence-supported algorithm Reasoning behind each recommendation Focus: evidence for efficacy Clinical experience is also important Based on evidence

Some specific concepts The importance of assessing comorbidities in PTSD The role of prazosin and trazodone in sleep management An update on how effective SSRIs really are for PTSD (we base this evaluation on effect sizes) How to manage treatment resistance

Some specific concepts The importance of assessing comorbidities in PTSD The role of prazosin and trazodone in sleep management An update on how effective SSRIs really are for PTSD (we base this evaluation on effect sizes) How to manage treatment resistance

Some specific concepts The importance of assessing comorbidities in PTSD The role of prazosin and trazodone in sleep management An update on how effective SSRIs really in for PTSD (we base this evaluation on effect sizes) How to manage treatment resistance

Some specific concepts The importance of assessing comorbidities in PTSD The role of prazosin and trazodone in sleep management An update on how effective SSRIs really are in PTSD (we base this evaluation on effect sizes) How to manage treatment resistance

Next Video: Differential Diagnosis of PTSD