Genetic Syndromes and Outcome After Surgical Correction of Tetralogy of Fallot Guido Michielon, MD, Bruno Marino, MD, Roberto Formigari, MD, Gaetano Gargiulo,

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Presentation transcript:

Genetic Syndromes and Outcome After Surgical Correction of Tetralogy of Fallot Guido Michielon, MD, Bruno Marino, MD, Roberto Formigari, MD, Gaetano Gargiulo, MD, Fernando Picchio, MD, Maria C. Digilio, MD, Silvia Anaclerio, MD, Gianluca Oricchio, MD, Stephen P. Sanders, MD, Roberto M. Di Donato, MD The Annals of Thoracic Surgery Volume 81, Issue 3, Pages 968-975 (March 2006) DOI: 10.1016/j.athoracsur.2005.09.033 Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Actuarial survival plot with 95% confidence limits after repair of tetralogy of Fallot in syndromic and nonsyndromic patients. (○ = nonsyndromic; ▵ = syndromic.) The Annals of Thoracic Surgery 2006 81, 968-975DOI: (10.1016/j.athoracsur.2005.09.033) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Kaplan-Meier survival plot with 95% confidence limits in syndromic and nonsyndromic patients with normal pulmonary artery anatomy. (○ = nonsyndromic; ▵ = syndromic.) The Annals of Thoracic Surgery 2006 81, 968-975DOI: (10.1016/j.athoracsur.2005.09.033) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Kaplan-Meier survival plot in syndromic patients stratified by type of genetic syndrome. (♢ = Down; ▵ = del22q11; ○ = other; □ = VACTERL.) The Annals of Thoracic Surgery 2006 81, 968-975DOI: (10.1016/j.athoracsur.2005.09.033) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

Fig 4 Kaplan-Meier freedom from any type of reintervention after complete repair of tetralogy of Fallot in syndromic and nonsyndromic patients. The 95% confidence limits are depicted in dotted lines. (○ = no syndrome; ▵ = syndrome.) The Annals of Thoracic Surgery 2006 81, 968-975DOI: (10.1016/j.athoracsur.2005.09.033) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions

Fig 5 Kaplan-Meier freedom from reoperation after complete tetralogy of Fallot repair in syndromic patients with normal pulmonary artery anatomy, stratified by type of surgical strategy. The 95% confidence limits are depicted in dotted lines. (○ = primary repair; ▵ = staged repair.) The Annals of Thoracic Surgery 2006 81, 968-975DOI: (10.1016/j.athoracsur.2005.09.033) Copyright © 2006 The Society of Thoracic Surgeons Terms and Conditions