Comparison of antioxidant activity of cilnidipine and amlodipine

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Presentation transcript:

Comparison of antioxidant activity of cilnidipine and amlodipine Keiichi Hishikawa, Osamu Takase, Mana Idei, Toshiro Fujito Kidney International Volume 76, Issue 2, Pages 230-231 (July 2009) DOI: 10.1038/ki.2009.146 Copyright © 2009 International Society of Nephrology Terms and Conditions

Figure 1 Comparative inhibitory effect of cilnidipine and amlodipine on superoxide production from cultured human mesangial cells (HMSCs). Cilnidipine (black circles) and amlodipine (red circles) were added at the same time with ionomycin to the incubation medium of HMSCs. Effects of pretreatment with cilnidipine and amlodipine are shown as triangles (cilnidipine, black triangles; amlodipine, red triangles). HMSCs were pretreated with cilnidipine or amlodipine 1h before ionomycin stimulation. *P<0.05 vs red circle. **P<0.05 vs black circle. Values are mean±s.e.m. (n=8). Kidney International 2009 76, 230-231DOI: (10.1038/ki.2009.146) Copyright © 2009 International Society of Nephrology Terms and Conditions