Cardiac phenotypes in mouse models of systemic lupus erythematosus (SLE). Cardiac phenotypes in mouse models of systemic lupus erythematosus (SLE). We.

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Cardiac phenotypes in mouse models of systemic lupus erythematosus (SLE). Cardiac phenotypes in mouse models of systemic lupus erythematosus (SLE). We include a decision tree to aid model choice based on the cellular mechanisms or tissue effect of interest, with a summary of the cardiac information available for each model. C3, complement-component 3 protein; GvHD, graft-versus-host disease; PD-1, programmed cell death 1; PD-L1, programmed death-ligand 1; R-848, resiquimod; lpr, lymphoproliferation; gld, generalized lymphoproliferative disease; DCs, dendritic cells; Th1, T-helper cell type 1; MI, myocardial infarction; RV, right ventricle; LV, left ventricle; MRL, Murphy Roths Large. Chandan Sanghera et al. Dis. Model. Mech. 2019;12:dmm036947 © 2019. Published by The Company of Biologists Ltd