Correlations between two measures of type I interferon activity and serum galectin-3-binding protein in the SLE-IFN-α (n=26) and HC-IFN-α (n=10) cohorts.

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Presentation transcript:

Correlations between two measures of type I interferon activity and serum galectin-3-binding protein in the SLE-IFN-α (n=26) and HC-IFN-α (n=10) cohorts. Correlations between two measures of type I interferon activity and serum galectin-3-binding protein in the SLE-IFN-α (n=26) and HC-IFN-α (n=10) cohorts. (A) The IFN-α protein-activity scores obtained using the Mx-1 gene reporter assay and (B) the calculated IFN-α scores representing gene expression of IFN-inducible genes in PBMCs correlated significantly with serum concentrations of galectin-3-binding protein. Non-parametric correlation analysis (Spearman's r) was used to estimate correlations. IFN-α, interferon-α; HC, healthy controls; SLE, systemic lupus erythematosus; PBMCs, peripheral blood mononuclear cells. Christoffer T Nielsen et al. Lupus Sci Med 2014;1:e000026 ©2014 by Lupus Foundation of America