GBM width (A), Vv(Mes/glom) (B), Vv(MM/glom) (C), Vv(MC/glom) (D), and Vv(MM/mes) (E) in one-kidney patients with (open diamond) and without (closed diamond) ACE inhibitor therapy and two-kidney patients with (open triangle) and without (closed triangle) ACE inhibitor therapy. GBM width (A), Vv(Mes/glom) (B), Vv(MM/glom) (C), Vv(MC/glom) (D), and Vv(MM/mes) (E) in one-kidney patients with (open diamond) and without (closed diamond) ACE inhibitor therapy and two-kidney patients with (open triangle) and without (closed triangle) ACE inhibitor therapy. The shaded area is 5 and 95% CI for the control subjects (A) and mean ± 2 SD for the control subjects (B–E). Shirley Chang et al. Diabetes 2008;57:1707-1711 ©2008 by American Diabetes Association