Maturation and apoptosis of human oocytes in vitro are age-related Ji Wu, M.D., Ph.D., Lizhu Zhang, M.D., Xiuyun Wang, M.D. Fertility and Sterility Volume 74, Issue 6, Pages 1137-1141 (December 2000) DOI: 10.1016/S0015-0282(00)01597-1
Figure 1 (A), Example of intact mature oocyte; (B,C), Examples of occurrence of cytoplasmic condensation and fragmentation. (Bar = 25 μm). Wu. Human oocyte maturation and apoptosis. Fertil Steril 2000. Fertility and Sterility 2000 74, 1137-1141DOI: (10.1016/S0015-0282(00)01597-1)
Figure 2 (A), The oocyte positively stained for DNA fragmentation (arrowhead) (×400). (B), Negative control had TDT omitted (×400). (C), The oocyte exhibited positive staining for the Fas antigen. (Bar = 25 μm.) (D), Negative control. (Bar = 25 μm.) Wu. Human oocyte maturation and apoptosis. Fertil Steril 2000. Fertility and Sterility 2000 74, 1137-1141DOI: (10.1016/S0015-0282(00)01597-1)