Francine M. Ducharme, MD, Megan E. Jensen, PhD, Morton J

Slides:

Advertisements

Similar presentations

Joint modeling of parentally reported and physician-confirmed wheeze identifies children with persistent troublesome wheezing Danielle C.M. Belgrave, MSc,

Advertisements

Early exposure to cow's milk protein is protective against IgE-mediated cow's milk protein allergy Yitzhak Katz, MD, Nelly Rajuan, MSc, Michael R. Goldberg,

Trends in hospitalizations for anaphylaxis, angioedema, and urticaria in Australia, to Leanne M. Poulos, BMedSc (Hons), Anne-Marie.

Jonathan A. Bernstein, MD, David M. Lang, MD, David A. Khan, MD

Association of physical activity, asthma, and allergies: A cohort of farming and nonfarming children Bettina Bringolf-Isler, MD, PhD, Eva Graf, MD, Marco.

Megan E. Jensen, PhD, Morton J

Risk of an asthma exacerbation after bariatric surgery in adults

Asthma exacerbations: Origin, effect, and prevention

Kyoung-Bok Min, MD, PhD, Jin-Young Min, PhD

Santa Jeremy Ono, BA, PhD, Mark B. Abelson, MD

Caregivers report a wide variety of early signs and symptoms of impending asthma exacerbations that are not different between preschool and school-aged.

Is 9 more than 2 also in allergic airway inflammation?

Probiotics during the first 7 years of life: A cumulative risk reduction of eczema in a randomized, placebo-controlled trial Marko Kalliomäki, MD, PhD,

Jonathan A. Bernstein, MD, David M. Lang, MD, David A. Khan, MD

Joe K. Gerald, MD, PhD, Roni Grad, MD, William C. Bailey, MD, Lynn B

Trends in hospitalizations for anaphylaxis, angioedema, and urticaria in Australia, to Leanne M. Poulos, BMedSc (Hons), Anne-Marie.

Mothers' anxiety during pregnancy is associated with asthma in their children Hannah Cookson, MB, ChB, Raquel Granell, PhD, Carol Joinson, PhD, Yoav Ben-Shlomo,

NAEPP Expert Panel Report

Lieuwe D. Bos, MSc, PhD, Peter J. Sterk, MD, PhD, Stephen J

Test for Respiratory and Asthma Control in Kids (TRACK): A caregiver-completed questionnaire for preschool-aged children Kevin R. Murphy, MD, Robert.

The risk of asthma exacerbation after stopping low-dose inhaled corticosteroids: A systematic review and meta-analysis of randomized controlled trials

Peter M. Wolfgram, MD, David B. Allen, MD

Etiology of asthma exacerbations

William J. Calhoun, MD, Tmirah Haselkorn, PhD, Dave P

Age-dependent effect of ambient ozone on emergency asthma hospitalizations in Hong Kong Yuanrong Dai, MD, Hong Qiu, PhD, Shengzhi Sun, PhD, Yang Yang,

Jewlya Lynn, PhD, Sophie Oppenheimer, MS, MPH, Lorena Zimmer, MA

Short- and long-term efficacy of prednisolone for first acute rhinovirus-induced wheezing episode Tuomas Jartti, MD, Riitta Nieminen, BM, Tytti Vuorinen,

Reply Journal of Allergy and Clinical Immunology

Jon Genuneit, MD, MSc Journal of Allergy and Clinical Immunology

Acute asthma intervention: Insights from the STAY study

Time for a paradigm shift in asthma treatment: From relieving bronchospasm to controlling systemic inflammation Leif Bjermer, MD Journal of Allergy.

Staphylococcus aureus colonization is associated with wheeze and asthma among US children and young adults Meghan F. Davis, PhD, Roger D. Peng, PhD,

What are the best outcome measurements for atopic eczema

Is eczema really on the increase worldwide?

Food allergy: A review and update on epidemiology, pathogenesis, diagnosis, prevention, and management Scott H. Sicherer, MD, Hugh A. Sampson, MD Journal.

Do oral corticosteroids reduce the severity of acute lower respiratory tract illnesses in preschool children with recurrent wheezing? Avraham Beigelman,

Increasing rate of hospitalizations for food-induced anaphylaxis in Italian children: An analysis of the Italian Ministry of Health database Rita Nocerino,

A cluster-randomized trial shows telephone peer coaching for parents reduces children's asthma morbidity Jane M. Garbutt, MB, ChB, Yan Yan, MD, PhD,

Claus Bachert, MD, PhD, Cezmi A. Akdis, MD

Endotyping early childhood asthma by quantitative symptom assessment

Lyndsey A. Darrow, PhD, Jeremy Hess, MD, Christine A

H. William Kelly, PharmD Journal of Allergy and Clinical Immunology

Autophagy: Nobel Prize 2016 and allergy and asthma research

Food allergy: Epidemiology, pathogenesis, diagnosis, and treatment

Diagnosis and management of early asthma in preschool-aged children

Geographic variability in childhood asthma prevalence in Chicago

High prevalence of severe asthma in a large random population study

Mary F. Linehan, PhD, Timothy L. Frank, MD, Michelle L

Syk expression and IgE-mediated histamine release in basophils as biomarkers for predicting the clinical efficacy of omalizumab Donald W. MacGlashan,

One step forward, 2 steps back: The enigma of preschool wheeze

Assessment of airflow limitation, airway inflammation, and symptoms during virus- induced wheezing episodes in 4- to 6-year-old children George N. Konstantinou,

A simulation model of building intervention impacts on indoor environmental quality, pediatric asthma, and costs Maria Patricia Fabian, ScD, Gary Adamkiewicz,

Day-care attendance, position in sibship, and early childhood wheezing: A population- based birth cohort study Nicolaos C. Nicolaou, MD, MPhil, Angela.

Fluctuation phenotyping based on daily fraction of exhaled nitric oxide values in asthmatic children Georgette Stern, MSc, Johan de Jongste, MD, Ralf.

Jessica H. Savage, MD, MHS, Elizabeth C. Matsui, MD, MHS, Robert A

Association of physical activity, asthma, and allergies: A cohort of farming and nonfarming children Bettina Bringolf-Isler, MD, PhD, Eva Graf, MD, Marco.

Pınar Uysal, MD, Esben Eller, MSc, PhD, Charlotte G

Päivi M. Salo, PhD, Samuel J. Arbes, DDS, MPH, PhD, Patrick W

Macrolide antibiotics and asthma treatment

Neil W. Johnston, MSc, Sebastian L. Johnston, MD, PhD, Joanne M

Asthma: The past, future, environment, and costs

Joint modeling of parentally reported and physician-confirmed wheeze identifies children with persistent troublesome wheezing Danielle C.M. Belgrave,

Environmental factors and eosinophilic esophagitis

The prevalence and natural course of food protein–induced enterocolitis syndrome to cow’s milk: A large-scale, prospective population-based study Yitzhak.

Advances in pediatric asthma in 2007

Negative affect, medication adherence, and asthma control in children

Omalizumab is effective in allergic and nonallergic patients with nasal polyps and asthma Philippe Gevaert, MD, PhD, Lien Calus, MD, Thibaut Van Zele,

Effect of codeine on objective measurement of cough in chronic obstructive pulmonary disease Jaclyn Smith, MD, PhD, Emily Owen, MPhil, John Earis, MD,

Natural history of cow’s milk allergy

Modeling asthma exacerbations through lung function in children

Presentation transcript:

Asthma Flare-up Diary for Young Children to monitor the severity of exacerbations Francine M. Ducharme, MD, Megan E. Jensen, PhD, Morton J. Mendelson, PhD, Patricia C. Parkin, MD, Eve Desplats, MSc, Xun Zhang, PhD, Robert Platt, PhD Journal of Allergy and Clinical Immunology Volume 137, Issue 3, Pages 744-749.e6 (March 2016) DOI: 10.1016/j.jaci.2015.07.028 Copyright © 2015 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 1 Selection of ADYC diaries for analyses of psychometric properties. Selection of ADYC diary sets, as per our a priori definitions, is presented in the graph. *Parents reported asthma flare-ups or suspected URTIs based on symptoms of runny or congested nose, sore throat, earache, and/or fever. †ADYC, Asthma Flare-up Diary for Young Children. ‡A valid ADYC diary set is defined as containing at least 2 consecutive days and no more than 1 missing or “cannot answer” item per day per episode. Journal of Allergy and Clinical Immunology 2016 137, 744-749.e6DOI: (10.1016/j.jaci.2015.07.028) Copyright © 2015 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 2 Discriminant validity of the ADYC. The mean cumulative scores on the 17-item ADYC (ie, the sum of each daily score [each item on a scale of 1-7]) throughout the duration of the episode are displayed with 95% CIs (error bars) for those that did or did not result in (1) an exacerbation, which was defined as 2 or more days with a minimum of 2 of 3 symptoms (cough, wheeze, and dyspnea) with a score of 2 or more on the 7-point scale, as recorded on the ADYC; (2) an acute care visit; (3) use of rescue oral corticosteroids; or (4) a hospital admission. Error bars represent 95% CIs around mean cumulative scores. †The group MD and 95% CI are reported at the top of each graph. Journal of Allergy and Clinical Immunology 2016 137, 744-749.e6DOI: (10.1016/j.jaci.2015.07.028) Copyright © 2015 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E1 The ADYC. The English version of the 17-item caregiver-completed ADYC questionnaire for children 1 to 6 years of age during an asthma exacerbation. Journal of Allergy and Clinical Immunology 2016 137, 744-749.e6DOI: (10.1016/j.jaci.2015.07.028) Copyright © 2015 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E2 Le Journal d'une crise d'asthme chez l'enfant. The French version of the 17-item caregiver-completed ADYC questionnaire for children 1 to 6 years of age during an asthma exacerbation. Journal of Allergy and Clinical Immunology 2016 137, 744-749.e6DOI: (10.1016/j.jaci.2015.07.028) Copyright © 2015 American Academy of Allergy, Asthma & Immunology Terms and Conditions